Abstract
The role of oxidative stress in breast cancer risk is still unclear. OGG1 encodes an 8-oxoguanine DNA glycosylase/AP lyase that catalyzes the removal of 8-oxodeoxyguanosine from DNA. 8-Oxodeoxyguanosine, the most abundant lesion generated by oxidative stress, is highly mutagenic. Environmental sources of oxidative stress, such as alcohol consumption, cigarette smoking, high body mass index (BMI), and low fruits and vegetables intake, may modify the association of genetic polymorphisms with breast cancer risk. We investigated the association between three genetic polymorphisms in OGG1 (Ser(326)Cys, 7143A/G, and 11657A/G) and breast cancer risk among 1,058 cases and 1,102 controls participating in the Long Island Breast Cancer Study Project. No associations were observed between individual OGG1 polymorphisms, haplotypes, or diplotypes and breast cancer. The association between having at least one variant allele and breast cancer risk was stronger among moderate alcohol drinkers for Ser(326)Cys [odds ratio (OR), 1.82; 95% confidence interval (95% CI), 1.06-3.10] relative to nondrinkers with the wild-type genotype and among those with higher BMI for 7143A/G (OR, 1.47; 95% CI, 1.10-1.96) and for 11657A/G (OR, 1.41; 95% CI, 1.05-1.88...Continue Reading
References
Apr 24, 1999·Biochimie·S Boiteux, J P Radicella
May 8, 1999·Molecular Biology of the Cell·K NishiokaY Nakabeppu
Mar 3, 2001·Cancer Causes & Control : CCC·P K VerkasaloT J Key
Mar 20, 2001·American Journal of Human Genetics·M StephensP Donnelly
Aug 29, 2001·Bioinformatics·D G Cox, F Canzian
May 7, 2002·International Journal of Cancer. Journal International Du Cancer·Toshiro TakezakiHaruhiko Sugimura
Jul 16, 2002·Carcinogenesis·Abul ElahiPhilip Lazarus
Sep 11, 2002·Breast Cancer Research and Treatment·Marilie D GammonG Iris Obrams
Jun 5, 2003·Breast Cancer Research and Treatment·Ji-Yeob ChoiDaehee Kang
Sep 30, 2003·Carcinogenesis·James A Mobley, Robert W Brueggemeier
Oct 24, 2003·American Journal of Human Genetics·Matthew Stephens, Peter Donnelly
Jan 28, 2004·Annual Review of Pharmacology and Toxicology·James E Klaunig, Lisa M Kamendulis
Dec 8, 2004·Molecular Carcinogenesis·J M WeissCornelia M Ulrich
Mar 1, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Amanda J LeeJames K Chipman
Dec 14, 2005·Carcinogenesis·Mary Beth TerryRegina M Santella
Citations
Jan 22, 2011·Rheumatology International·Shih-Yin ChenFuu-Jen Tsai
Oct 9, 2007·Breast Cancer Research and Treatment·Suleeporn SangrajrangOdilia Popanda
Jan 9, 2010·Breast Cancer Research and Treatment·Weiguang YuanDianjun Li
Jan 8, 2010·Breast Cancer Research and Treatment·Dongying GuJinfei Chen
Jun 24, 2008·Journal of Toxicology and Environmental Health. Part a·Hans-Peter RihsThomas Bruning
Nov 29, 2011·Mutagenesis·Wei WangZhengdong Zhang
Dec 14, 2011·Urologia Internationalis·Dawei LiZhonghua Xu
Feb 26, 2010·Annals of Surgical Oncology·Hsu Ming-ShieanChun-Wen Cheng
Apr 5, 2014·PLoS Genetics·Ana OsorioJavier Benitez
Nov 25, 2011·PloS One·Bingbing WeiPeng Lu
Dec 10, 2008·Arhiv za higijenu rada i toksikologiju·Bensu KarahalilAli Esat Karakaya
Jun 5, 2014·Diagnostic Pathology·Qiliu PengShan Li
Nov 25, 2014·BMC Cancer·Patricia RodriguesPilar Eroles
Jan 27, 2012·Journal of Atherosclerosis and Thrombosis·Hann-Yeh ShyuChun-Wen Cheng
Jul 5, 2011·Archives of Medical Research·Zheng LiDong Wang
Mar 8, 2011·Mutation Research·Justyna JanikElżbieta Speina
Mar 4, 2008·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Marilie D Gammon, Regina M Santella
Apr 16, 2008·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Ching-Yu YenHsueh-Wei Chang
Mar 6, 2012·Pediatric Blood & Cancer·Philip J LupoMichael E Scheurer
Apr 6, 2011·Molecular Carcinogenesis·Minkyo SongDaehee Kang
Mar 8, 2016·International Journal of Cancer. Journal International Du Cancer·Irina MordukhovichMarilie D Gammon
Mar 13, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Hao LuoDong Wang
Feb 24, 2015·Annals of Epidemiology·Lauren E McCulloughMarilie D Gammon
Feb 2, 2013·The Breast : Official Journal of the European Society of Mastology·Hui XieXiaoxiang Chen
Oct 12, 2011·Mutation Research·Anil KumarShashi Khandelwal
Jan 16, 2015·Medical Oncology·Ping-Ting ZhouChun-Fang Gao
Nov 9, 2016·Pathology Oncology Research : POR·Mohammed AlanaziNarasimha Reddy Parine
Jun 14, 2017·The Breast Journal·Ali Sanjari MoghaddamAlireza Mosavi Jarrahi
Dec 15, 2010·Breast Cancer Research and Treatment·Xiaoxiang ChenYaping Wang
Apr 19, 2017·Oncotarget·Sang Wook KangJu Yeon Ban
May 6, 2017·PloS One·Yaou RenYuan Liu
Mar 30, 2016·World Journal of Gastroenterology : WJG·Ching-Yu LaiChih-Ching Yeh
Apr 18, 2018·Oncotarget·Lele QiaoMengxiang Li
Jan 16, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Maosheng HuangXifeng Wu
Jul 17, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Haixin LiKexin Chen
Jan 1, 2020·Non-coding RNA Research·Zainularifeen Abduljaleel