Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar)

The British Journal of Nutrition
M B BetancorR E Olsen

Abstract

Facing a bottleneck in the growth of aquaculture, and a gap in the supply and demand of the highly beneficial n-3 long-chain PUFA (LC-PUFA), sustainable alternatives to traditional marine-based feeds are required. Therefore, in the present trial, a novel oil obtained from a genetically engineered oilseed crop, Camelina sativa, that supplied over 25 % n-3 LC-PUFA was tested as a sole dietary-added lipid source in Atlantic salmon (Salmo salar) feed. Three groups of fish were fed three experimental diets for 12 weeks with the same basal composition and containing 20 % added oil supplied by either a blend of fish oil and rapeseed oil (1:3) (COM) reflecting current commercial formulations, wild-type Camelina oil (WCO) or the novel transgenic Camelina oil (TCO). There were no negative effects on the growth, survival rate or health of the fish. The whole fish and flesh n-3 LC-PUFA levels were highest in fish fed TCO, with levels more than 2-fold higher compared with those of fish fed the COM and WCO diets, respectively. Diet TCO had no negative impacts on the evaluated immune and physiological parameters of head kidney monocytes. The transcriptomic responses of liver and mid-intestine showed only mild effects on metabolism genes. Over...Continue Reading

References

Oct 1, 1990·Diabetes Research and Clinical Practice·J L LoganS M Lee
Aug 2, 2003·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Matthew P BransdenPeter D Nichols
Apr 9, 2004·The Proceedings of the Nutrition Society·Parveen Yaqoob
May 4, 2004·Prostaglandins, Leukotrienes, and Essential Fatty Acids·George MamalakisAnthony Kafatos
Nov 1, 2005·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·R GangaM S Izquierdo
Feb 3, 2006·Journal of Immunoassay & Immunochemistry·Hyung Sim ChoiChaekyun Kim
Jun 19, 2007·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Tor GjøenBente Ruyter
Jul 26, 2011·Developmental and Comparative Immunology·Lluis Tort
Dec 27, 2011·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Sofia MoraisJ Gordon Bell
May 25, 2012·The British Journal of Nutrition·Javier Delgado-ListaFrancisco Perez-Jimenez
Dec 7, 2013·The Plant Journal : for Cell and Molecular Biology·Noemi Ruiz-LopezOlga Sayanova
May 5, 2016·Nucleic Acids Research·Maxim V KuleshovAvi Ma'ayan
Oct 19, 2017·The Proceedings of the Nutrition Society·P C Calder

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Citations

Jul 11, 2019·Planta·Antonella SuccurroTimothy O Jobe
Jul 1, 2020·Frontiers in Plant Science·James R PetrieSurinder P Singh
Jul 9, 2020·Progress in Lipid Research·Sandra M CorreaYariv Brotman
Oct 4, 2020·Progress in Lipid Research·Houguo XuQinghui Ai
Jun 29, 2021·The Plant Journal : for Cell and Molecular Biology·Baptiste CastelJonathan D G Jones

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