PMID: 8944765Nov 1, 1996Paper

Ole e 3, an olive-tree allergen, belongs to a widespread family of pollen proteins

European Journal of Biochemistry
E BataneroR Rodríguez

Abstract

An allergen has been isolated from a saline extract of olive tree (Olea europaea) pollen. The protein consists of a single polypeptide chain of 9.2-kDa, as determined by mass spectrometry. It contains neither tryptophan nor tyrosine residues, and displays an acidic isoelectric point. The secondary structure of the protein, estimated from the analysis of the circular-dichroism spectrum in the peptide-bond region, is composed of 52% alpha-helix, 10% beta-strand, 29% beta-turn and 9% non-regular conformation. The N-terminal end of the protein is blocked. Amino-acid-sequence data have been obtained from peptides produced by CNBr treatment of the native allergen. A partial sequence of 36 amino acids has thus been elucidated. The protein exhibits sequence similarity with pollen allergens from Brassica species and contains a Ca(2+)-binding motif. The isolated protein displays IgE-binding activity against sera of patients allergic to olive-tree pollen. It has been named Ole e 3, according to the recommendations of the IUIS Nomenclature Committee. IgG ELISA inhibition assays with polyclonal antibodies specific for Ole e 3 reveal the presence of proteins similar to Ole e 3 in the pollen from non-related plant species, which may explain a...Continue Reading

References

Dec 1, 1992·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A W Wheeler
Oct 1, 1991·The Journal of Allergy and Clinical Immunology·C EbnerD Kraft
Jan 1, 1989·Annual Review of Biochemistry·N C Strynadka, M N James
Oct 15, 1988·European Journal of Biochemistry·L Menéndez-AriasR Rodríguez
Jan 1, 1982·International Archives of Allergy and Applied Immunology·C VelaC Lahoz
Sep 1, 1983·Clinical Allergy·M BlancaI Gonzalez-Reguera
Jan 1, 1994·International Archives of Allergy and Immunology·E Martín-OrozcoR Rodriguez
Apr 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T M ObispoM Lombardero
Jan 1, 1993·International Archives of Allergy and Immunology·S VrtalaR Valenta
Sep 15, 1993·European Journal of Biochemistry·M VillalbaR Rodríguez

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Citations

Jul 31, 2004·Current Allergy and Asthma Reports·Richard W Weber
Feb 14, 2004·Methods : a Companion to Methods in Enzymology·Petra Verdino, Walter Keller
Feb 26, 1999·Journal of Immunological Methods·L BoludaE Fernández-Caldas
Feb 12, 2000·The Journal of Allergy and Clinical Immunology·B CardabaC Lahoz
Apr 7, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Patricia BarralEva Batanero
Dec 25, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jason F White, David I Bernstein
May 10, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Rodrigo BarderasMayte Villalba
May 10, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Esther CompésMayte Villalba
Aug 2, 2000·Allergy·E M GonzálezR Rodríguez
Dec 8, 2004·International Archives of Allergy and Immunology·Nadine MothesRudolf Valenta
Apr 8, 2006·International Archives of Allergy and Immunology·Oscar DuffortFlorentino Polo
Jun 26, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R ValentaH Grönlund
Aug 24, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C AfferniC Pini
Oct 10, 2002·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A LedesmaR Rodríguez
Feb 6, 2007·Immunology and Allergy Clinics of North America·Nicole WopfnerPeter Lackner
Dec 26, 2006·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Rosalía RodríguezGuillermo Salamanca
Jan 26, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E G MarazuelaE Batanero
Feb 8, 2005·The Journal of Allergy and Clinical Immunology·Rodrigo BarderasMayte Villalba
Sep 14, 1999·The Journal of Allergy and Clinical Immunology·J Cuesta-HerranzJ Martínez
Oct 16, 1999·The Journal of Allergy and Clinical Immunology·M L TejeraR Rodríguez
Sep 20, 2005·Journal of Biotechnology·Patricia BarralRosalía Rodríguez
May 8, 2016·Journal of Ethnopharmacology·Ashutosh SharmaMaría Luisa Villarreal
Aug 14, 2002·Allergy·J Carnés, E Fernández-Caldas
Aug 14, 2002·Allergy·R RodríguezA Ledesma

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