PMID: 14644186Dec 4, 2003

Olefin metathesis in glycobiology: new routes towards diverse neoglycoconjugates

Current Opinion in Chemical Biology
Michiel A LeeuwenburghHerman S Overkleeft


This report provides a historical overview of the implementation of olefin metathesis in carbohydrate chemistry, with the emphasis on the construction of neoglycoconjugates. The current state-of-the-art in catalyst design allows the preparation of carbohydrate-containing molecules with great structural and functional diversity. Recent examples of complex neoglycoconjugates, including glycopolymers, glycoclusters, glycopeptide and glycolipid analogues are highlighted. Finally, future perspectives in the scope of olefin metathesis mediated neoglycoconjugate synthesis are discussed.


Jun 9, 2001·The Journal of Organic Chemistry·M C Hewitt, P H Seeberger
Jun 25, 2002·Chemistry & Biology·Marian C BryanChi-Huey Wong
Jul 6, 2002·Organic Letters·Robert M OwenLaura L Kiessling
Oct 12, 2002·Organic Letters·Glenn J McGarveyFrank W Schmidtmann
Oct 24, 2002·Chemistry : a European Journal·Guang-wu Chen, Andreas Kirschning
May 6, 2003·Angewandte Chemie·Stephen J Connon, Siegfried Blechert


Jun 2, 2005·Chemical Communications : Chem Comm·Simon Dorner, Bernhard Westermann
Mar 17, 2010·Current Opinion in Chemical Biology·Bernd LepeniesP H Seeberger
May 13, 2015·Glycoconjugate Journal·Misako TaichiKatsunori Tanaka
Feb 2, 2007·Advanced Synthesis & Catalysis·Joseph B BinderRonald T Raines
Nov 22, 2007·Journal of Peptide Science : an Official Publication of the European Peptide Society·Petr NiederhafnerJan Jezek
Feb 7, 2009·Chemistry : a European Journal·Dirk SchoepsHerbert Plenio
Feb 14, 2013·Organic & Biomolecular Chemistry·Maria Cristina BellucciAlessandro Volonterio

Related Concepts

Biochemical Phenomena
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