Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study.

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Chenghao QiuH. Lu

Abstract

To evaluate the prevalence and characteristics of olfactory or gustatory dysfunction in coronavirus disease 2019 (COVID-19) patients. Multicenter case series. Five tertiary care hospitals (3 in China, 1 in France, 1 in Germany). In total, 394 polymerase chain reaction (PCR)-confirmed COVID-19-positive patients were screened, and those with olfactory or gustatory dysfunction were included. Data including demographics, COVID-19 severity, patient outcome, and the incidence and degree of olfactory and/or gustatory dysfunction were collected and analyzed. The Questionnaire of Olfactory Disorders (QOD) and visual analog scale (VAS) were used to quantify olfactory and gustatory dysfunction, respectively. All subjects at 1 hospital (Shanghai) without subjective olfactory complaints underwent objective testing. Of 394 screened subjects, 161 (41%) reported olfactory and/or gustatory dysfunction and were included. Incidence of olfactory and/or gustatory disorders in Chinese (n = 239), German (n = 39), and French (n = 116) cohorts was 32%, 69%, and 49%, respectively. The median age of included subjects was 39 years, 92 of 161 (57%) were male, and 10 of 161 (6%) were children. Of included subjects, 10% had only olfactory or gustatory sympto...Continue Reading

References

May 11, 2004·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Johannes Frasnelli, Thomas Hummel
Jan 30, 2020·The New England Journal of Medicine·Qun LiZijian Feng
Feb 20, 2020·The New England Journal of Medicine·Lirong ZouJie Wu
Feb 26, 2020·International Journal of Oral Science·Hao XuQianming Chen
Mar 28, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Andrea GiacomelliMassimo Galli
Apr 8, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jerome R LechienSven Saussez
Apr 9, 2020·JAMA Otolaryngology-- Head & Neck Surgery·Michael EliezerCorinne Eloit
Apr 13, 2020·International Forum of Allergy & Rhinology·Carol H YanAdam S DeConde
Apr 25, 2020·Nature Medicine·Waradon SungnakUNKNOWN HCA Lung Biological Network
Apr 29, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Rachel KayeJames C Denneny

❮ Previous
Next ❯

Citations

Sep 11, 2020·Journal of Tropical Pediatrics·Prateek Kumar PandaLesa Dawman
Sep 17, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Vimal Kumar PaliwalNidhi Tejan
Oct 14, 2020·Current Allergy and Asthma Reports·Khang Wen PangChew Lip Ng
Dec 7, 2020·Journal of Tropical Pediatrics·Sharmila RamtekeJyotsna Shrivastava
Jan 16, 2021·Acta Odontologica Scandinavica·Nicola CirilloLorenzo Lo Muzio
Dec 23, 2020·The American Journal of the Medical Sciences·Muhammad AzizAbhilash Perisetti
Feb 2, 2021·Human Factors·E Leslie CameronKeith S Karn
Feb 10, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kai Liu, Zhenkun Yu
Jan 22, 2021·International Journal of Pediatric Otorhinolaryngology·Lakshit KumarA K Pandey
Jan 26, 2021·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Kunal ThakurArjun Gupta
Nov 3, 2020·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Naveed Nazir ShahMariya Ali
Feb 10, 2021·Current Opinion in Allergy and Clinical Immunology·Philip W RouadiJean Bousquet
May 15, 2021·Journal of Oral Microbiology·Monique Melo CostaLionel Almeras
Jul 1, 2021·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Alberto Martin-MartinezPere Clavé
Jun 26, 2021·EMBO Molecular Medicine·Guilherme Dias de MeloHervé Bourhy
Jul 15, 2021·ACS Chemical Neuroscience·Vitalakumar DS J S Flora
Jan 15, 2021·The Laryngoscope·Yury RusetskyUlyana Malyavina
Aug 20, 2021·Frontiers in Aging Neuroscience·Brianne N Sullivan, Tracy Fischer
Aug 28, 2021·Diagnostics·Monique Melo CostaLionel Almeras
Sep 9, 2021·Oral Diseases·Sandra López-VerdínMarco Meleti
Nov 5, 2021·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Aida KusiakDaniela Alterio
Sep 12, 2020·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Rafal Butowt, Christopher S von Bartheld
Sep 1, 2021·Disaster Medicine and Public Health Preparedness·Yanmei ZhaoShike Hou
Jan 14, 2022·American Journal of Physical Medicine & Rehabilitation·Eric A LiuSara J Cuccurullo
Jan 14, 2022·Cancer Metastasis Reviews·David G MenterAnil K Sood

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Software Mentioned

SPSS ( Statistical Package for the Social Sciences )

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.