PMID: 7545486Jun 1, 1995Paper

Oligoclonal beta-galactoside-specific gamma immunoglobulins allow the immunocytochemical detection of cellular antigenic determinants expressed in mouse brain after surgical injury

Neurochemistry International
R Joubert-CaronD Bladier

Abstract

Histological brain sections were probed with human oligoclonal lectin-like IgGs (L-IgG) purified from normal serum. In intact brain, antigenic determinants for these IgG were restricted to some blood vessel endothelial cells. By contrast, during the inflammatory reaction following a surgical injury, these determinants were detected at the cell surface of different cell types, within and near the lesion site. The cells reacting with L-IgG consisted of endothelial cell, mature astrocytes, activated microglial and ependymal cells.

References

Sep 1, 1991·Journal of the Neurological Sciences·H EloumamiD Bladier
Mar 1, 1989·Archives of Biochemistry and Biophysics·D BladierM Caron
Jan 1, 1988·Glia·W J StreitG W Kreutzberg
Jul 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J J MarchalonisS F Schluter
Jan 1, 1991·Neurochemistry International·D BladierJ Rossier

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