Oligodendroglia-lineage cells in brain plasticity, homeostasis and psychiatric disorders

Current Opinion in Neurobiology
F BireyA Aguirre

Abstract

Adult oligodendrocyte progenitor cells are uniformly distributed in both gray and white matter, displaying robust proliferative and migratory potential during health and disease. Recently, developments in new experimental approaches have brought about several novel insights about NG2-glia and myelinating oligodendrocytes, indicating a diverse toolkit of functions in experience-dependent myelination and homeostasis in the adult CNS. In this review, we summarize some of the topical studies that highlight newly emerging findings implicating oligodendroglia-lineage cells in brain plasticity, homeostasis and pathophysiology of neuropsychiatric disorders.

Citations

Mar 25, 2020·Journal of the American Heart Association·Matthew K TobinOrly Lazarov
Jul 15, 2020·The Journal of Pharmacology and Experimental Therapeutics·Alexandros G Kokkosis, Stella E Tsirka
May 20, 2018·Nature Reviews. Neuroscience·Dylan LaugBenjamin Deneen
Nov 5, 2019·Neuroscience·Vitor S AlvesFernando A Oliveira

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