PMID: 11908974Mar 23, 2002Paper

Oligomeric acylphloroglucinols from myrtle (Myrtus communis)

Journal of Natural Products
Giovanni AppendinoSimon Gibbons

Abstract

The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.

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