Oligonucleotide (GTG)5 as an epidemiological tool in the study of nontuberculous mycobacteria.

Journal of Clinical Microbiology
F J CilliersP D van Helden

Abstract

Analysis of restriction fragment length polymorphisms in the genome of Mycobacterium tuberculosis (DNA fingerprinting) has proved to be a useful epidemiological tool in the study of tuberculosis within populations or communities. However, to date, no similar method has been developed to study the epidemiology of nontuberculous mycobacteria (NTM). In this communication, we report that a simple oligonucleotide repeat, (GTG)5, can be used to accurately genotype all species and strains of NTM tested. We suggest that this technology is an easily applied and accurate tool which can be used for the study of the epidemiology of NTM.

References

May 1, 1992·Research in Microbiology·J D van EmbdenP W Hermans
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Jan 1, 1984·Microbiology and Immunology·B W JinZ Yoshii
May 1, 1994·Journal of Clinical Microbiology·I J WiidP D van Helden
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Aug 1, 1993·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·P Godfrey-FaussettL Clancy

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Citations

May 1, 2007·Personalized Medicine·Cedric J WerelyPaul D van Helden
Nov 21, 2009·Microbiology·Caroline CayrouMichel Drancourt
Feb 22, 2012·Molecular Biology Reports·Arkadiusz WojtasikPaweł Parniewski
May 19, 2006·Letters in Applied Microbiology·M I MatshekaB G Elisha
Oct 10, 2002·Clinics in Chest Medicine·Joseph O Falkinham

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