Abstract
Olive oil intake has been associated with lower risk of cardiovascular disease (CVD) in Mediterranean populations, but little is known about these associations in the U.S population. This study sought to examine whether olive oil intake is associated with total CVD, coronary heart disease (CHD), and stroke risk. This study included 61,181 women from the Nurses' Health Study (1990 to 2014) and 31,797 men from the Health Professionals Follow-up Study (1990 to 2014) who were free of cancer, heart disease, and stroke at baseline. Diet was assessed using food frequency questionnaires at baseline and then every 4 years. Cox proportional hazards regressions were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). During 24 years of follow-up, this study documented 9,797 incident cases of CVD, including 6,034 CHD cases and 3,802 stroke cases. After adjusting for major diet and lifestyle factors, compared with nonconsumers, those with higher olive oil intake (>0.5 tablespoon/day or >7 g/day) had 14% lower risk of CVD (pooled HR: 0.86; 95% CI: 0.79 to 0.94) and 18% lower risk of CHD (pooled HR: 0.82; 95% CI: 0.73 to 0.91). No significant associations were observed for total or ischemic stroke. Replacing 5 g/day of ma...Continue Reading
References
May 15, 1992·American Journal of Epidemiology·E B RimmW C Willett
Apr 25, 1987·Lancet·A Keys
Feb 1, 1997·Journal of Women's Health·G A ColditzS E Hankinson
May 1, 2002·International Journal of Epidemiology·E Fernández-JarneM A Martínez-González
Dec 17, 2004·The New England Journal of Medicine·Jennifer K PaiEric B Rimm
Oct 4, 2007·Molecular Nutrition & Food Research·Audrey C Tierney, Helen M Roche
Apr 15, 2009·Archives of Internal Medicine·Andrew MenteSonia S Anand
Oct 28, 2009·Journal of Cardiovascular Pharmacology·María-Isabel CovasMontserrat Fitó
Mar 31, 2010·PLoS Medicine·Dariush MozaffarianSarah Wallace
Dec 24, 2010·The American Journal of Clinical Nutrition·Benedetta BendinelliSalvatore Panico
Jan 11, 2011·Maturitas·Miguel Ruiz-Canela, Miguel A Martínez-González
Jun 1, 2012·The American Journal of Clinical Nutrition·Genevieve BucklandCarlos A Gonzalez
Aug 17, 2012·The British Journal of Nutrition·Vardis DilisAntonia Trichopoulou
Sep 26, 2012·The British Journal of Nutrition·Genevieve BucklandCarlos A Gonzalez
Nov 29, 2012·American Journal of Epidemiology·Gesthimani MisirliAntonia Trichopoulou
Apr 30, 2014·The British Journal of Nutrition·Miguel A Martínez-GonzálezMiguel Delgado-Rodríguez
Jun 3, 2014·BMC Medicine·Marta Guasch-FerréJordi Salas-Salvadó
Mar 3, 2017·The American Journal of Clinical Nutrition·Didier BrassardBenoît Lamarche
Oct 17, 2017·American Journal of Epidemiology·Changzheng YuanWalter C Willett
Mar 23, 2018·The American Journal of Clinical Nutrition·Geng ZongQi Sun
Jun 14, 2018·The New England Journal of Medicine·Ramón EstruchUNKNOWN PREDIMED Study Investigators
Oct 12, 2018·Diabetologia·Jun LiShelley S Tworoger
Jan 29, 2019·Circulation Research·Marta Guasch-FerréQi Sun
Apr 21, 2019·The Lancet. Diabetes & Endocrinology·Ramon EstruchUNKNOWN PREDIMED Study Investigators
Sep 5, 2019·Nutrients·José J GaforioAristidis M Tsatsakis
Citations
May 8, 2020·Circulation Research·Francesco VioliRoberto Carnevale
Apr 23, 2020·Nutrients·Yu-Jin KwonJi-Won Lee
Jul 2, 2020·Foods·Esther Sendra
Sep 5, 2020·Nutrients·Elke A Trautwein, Sue McKay
Nov 18, 2020·International Journal of Stroke : Official Journal of the International Stroke Society·Dimitrios SagrisHaralampos Milionis
Dec 2, 2020·Nutrients·Mercedes Sotos-PrietoStefanos N Kales
Dec 8, 2020·Journal of Medical Internet Research·Leticia GoniMiguel Ruiz-Canela
Nov 13, 2020·The Journal of Clinical Endocrinology and Metabolism·Milena Monfort-PiresLicio A Velloso
Dec 15, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Fernando Martins do ValeHenrique Atalaia Barbacena
Feb 6, 2021·Postgraduate Medical Journal·Tao YouXiang Zhou
Aug 10, 2020·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Clara Gómez-DonosoMaira Bes-Rastrollo
Apr 18, 2020·Journal of the American College of Cardiology·Ramon EstruchEmilio Ros
Feb 20, 2021·Journal of the American College of Cardiology·Valentin Fuster
Apr 16, 2021·BMC Medicine·Yu ZhangJingjing Jiao
Aug 1, 2020·Journal of the American College of Cardiology·Massimo Leggio, Furio Colivicchi
Aug 1, 2020·Journal of the American College of Cardiology·Muddassir Mehmood
Aug 1, 2020·Journal of the American College of Cardiology·Marta Guasch-Ferré, Frank B Hu
May 8, 2021·Current Cardiology Reports·Niki KatsikiJose Lopez-Miranda
Jun 19, 2021·Nutrition and Health·Zamzam PaknahadParvin Rajabi
Jul 7, 2021·Cardiovascular Research·Gabriele RiccardiOlga Vaccaro
Aug 5, 2021·Journal of the American Heart Association·Andrea J GlennJohn L Sievenpiper
Aug 24, 2021·Journal of Internal Medicine·M Guasch-Ferré, W C Willett
Oct 14, 2021·International Orthopaedics·Yan LuoPeifu Tang