Olive oil lessened fatty liver severity independent of cardiometabolic correction in patients with non-alcoholic fatty liver disease: A randomized clinical trial

Nutrition
Shahla RezaeiReza Barati Boldaji

Abstract

Olive oil has health benefits for the correction of metabolic diseases. We aimed to evaluate the effect of olive oil consumption on the severity of fatty liver and cardiometabolic markers in patients with non-alcoholic fatty liver disease. This randomized, double-blind, clinical trial was conducted on 66 patients with non-alcoholic fatty liver disease. Patients were divided to receive either olive or sunflower oil, each 20 g/d for 12 wk. A hypocaloric diet (-500 kcal/d) was recommended to all participants. Fatty liver grade, liver enzymes, anthropometric parameters, blood pressure, serum lipid profile, glucose, insulin, malondialdehyde, total antioxidant capacity, and interleukin-6 were assessed pre- and postintervention. Fatty liver grade, weight, waist circumference, and blood pressure significantly decreased in both groups. Sunflower oil significantly reduced serum aspartate and alanine aminotransferases and olive oil only decreased serum aspartate aminotransferase. Fat-free mass and skeletal muscle mass significantly reduced after the consumption of sunflower oil and serum triacylglycerols and fat mass significantly declined after the ingestion of olive oil. Among these variables, only changes in fatty liver grade (-0.29 ± ...Continue Reading

Citations

Mar 25, 2019·Nutrients·Carolina M PerdomoJavier Escalada
Jun 20, 2019·Expert Review of Gastroenterology & Hepatology·Ludovico AbenavoliAngelo Maria Giuffrè
Feb 23, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Genoveva Berná, Manuel Romero-Gomez
Jun 12, 2021·The Cochrane Database of Systematic Reviews·Elena BuzzettiKurinchi Selvan Gurusamy

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