PMID: 15333722Aug 31, 2004Paper

Olive oils high in phenolic compounds modulate oxidative/antioxidative status in men

The Journal of Nutrition
Tanja WeinbrennerMaria-Isabel Covas

Abstract

The aim of the present study was to evaluate whether olive oils high in phenolic compounds influence the oxidative/antioxidative status in humans. Healthy men (n = 12) participated in a double-blind, randomized, crossover study in which 3 olive oils with low (LPC), moderate (MPC), and high (HPC) phenolic content were given as raw doses (25 mL/d) for 4 consecutive days preceded by 10-d washout periods. Volunteers followed a strict very low-antioxidant diet the 3 d before and during the intervention periods. Short-term consumption of olive oils decreased plasma oxidized LDL (oxLDL), 8-oxo-dG in mitochondrial DNA and urine, malondialdehyde in urine (P < 0.05 for linear trend), and increased HDL cholesterol and glutathione peroxidase activity (P < 0.05 for linear trend), in a dose-dependent manner with the phenolic content of the olive oil administered. At d 4, oxLDL after MPC and HPC, and 8-oxo-dG after HPC administration (25 mL, respectively), were reduced when the men were in the postprandial state (P < 0.05). Phenolic compounds in plasma increased dose dependently during this stage with the phenolic content of the olive oils at 1, 2, 4, and 6 h, respectively (P < 0.01). Their concentrations increased in plasma and urine samples...Continue Reading

References

Jan 18, 1995·Journal of the National Cancer Institute·A TrichopoulouD Trichopoulos
Jun 1, 1995·The American Journal of Clinical Nutrition·S RenaudP Toubol
Jun 1, 1996·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·S Loft, H E Poulsen
Sep 8, 1998·Journal of Applied Physiology·M A FergusonJ L Durstine
Sep 2, 1999·Biochemical and Biophysical Research Communications·A RehmanC A Rice-Evans
May 10, 2000·Biochimica Et Biophysica Acta·J P De La CruzF Sánchez de la Cuesta
Nov 4, 2000·The American Journal of Clinical Nutrition·E M KurowskaP Serratore
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
May 30, 2001·European Journal of Clinical Nutrition·M N VissersM B Katan
Jun 16, 2001·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·M A Mangas-CruzP P García-Luna
Feb 22, 2002·European Journal of Clinical Nutrition·E GimenoM C López-Sabater
Jul 13, 2002·International Journal of Cancer. Journal International Du Cancer·Kazuhiro SuzukiHidetoshi Yamanaka
Jul 30, 2002·The American Journal of Clinical Nutrition·Peter Møller, Steffen Loft
Oct 10, 2002·European Journal of Clinical Nutrition·J MoschandreasA Kafatos
Feb 1, 2003·Lipids·Sheila A WisemanFrans H M M van de Put
Apr 23, 2003·Hypertension·Josep RedónGuillermo T Sáez
May 7, 2003·Atherosclerosis·Tanja WeinbrennerJaume Marrugat
May 27, 2003·Clinical Chemistry·Elisabet Miro-CasasRafael de la Torre
Jun 12, 2003·Life Sciences·Hyun-Ju SeoMyung-Sook Choi
May 29, 2004·European Journal of Nutrition·Jaume MarrugatUNKNOWN SOLOS Investigators

❮ Previous
Next ❯

Citations

Sep 21, 2007·Molecular Nutrition & Food Research·Montserrat FitóMaría-Isabel Covas
Oct 4, 2007·Molecular Nutrition & Food Research·Maria Annunziata CarluccioRaffaele De Caterina
Sep 21, 2007·Molecular Nutrition & Food Research·Francisco Pérez-JiménezJose Lopez-Miranda
Oct 25, 2008·Critical Reviews in Food Science and Nutrition·Gregory Tucker, Kevin Robards
Nov 4, 2008·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Valentina GalloPaolo Vineis
Mar 18, 2009·Omics : a Journal of Integrative Biology·Olha KhymenetsRafael de la Torre
Jun 19, 2009·Molecular Nutrition & Food Research·Roberto FabianiGuido Morozzi
May 13, 2010·Natural Product Research·Santosh K ShuklaSuman B Sharma
Sep 6, 2012·European Journal of Clinical Nutrition·H E BaysJ W Anderson
Mar 2, 2013·Molecular Nutrition & Food Research·Sandra Martín-PeláezIgor Pravst
Dec 22, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lisa Parkinson, Sara Cicerale
Mar 25, 2017·Nutrients·Julien PeyrolMarie Josèphe Amiot
May 27, 2020·Cardiovascular Therapeutics·Flavia FranconiAnnalisa Romani
Jun 3, 2005·The Journal of Nutrition·Catherine M BitlerRoberto Crea
Mar 31, 2006·The British Journal of Nutrition·Simonetta SalviniDomenico Palli
May 19, 2006·Journal of Thrombosis and Haemostasis : JTH·Y M PachecoF J G Muriana
May 9, 2009·Omics : a Journal of Integrative Biology·Valentini KonstantinidouMontserrat Fito
Oct 19, 2006·Current Atherosclerosis Reports·Colin D KaySheila G West
Jun 17, 2008·European Journal of Nutrition·Steffen LoftRyszard Olinski
Apr 14, 2010·International Journal of Molecular Sciences·Sara CiceraleRussell Keast
Dec 4, 2008·Molecular Nutrition & Food Research·Catherine ItsiopoulosMary Kaimakamis
Sep 18, 2009·The American Journal of Clinical Nutrition·Helmut SchröderUNKNOWN PREDIMED Study Investigators
Dec 17, 2009·Molecular Nutrition & Food Research·Rosa SirianniVincenzo Pezzi
Jul 29, 2011·Phytotherapy Research : PTR·Dezheng GongLaifu Zhong
Feb 7, 2014·Critical Reviews in Food Science and Nutrition·Vildan Uylaşer, Gökçen Yildiz
Oct 10, 2014·European Journal of Nutrition·Paola PrioreGabriele V Gnoni
Sep 2, 2016·BioFactors·Marta PiroddiFrancesco Galli
Nov 25, 2016·BioMed Research International·Mariangela RondanelliSimone Perna
Mar 30, 2007·The British Journal of Nutrition·Yolanda M PachecoFrancisco J G Muriana
Dec 19, 2006·American Journal of Physiology. Heart and Circulatory Physiology·S J RietjensG R M M Haenen
Dec 19, 2008·Critical Reviews in Food Science and Nutrition·Sara CiceraleRussell S J Keast
Oct 28, 2009·Journal of Cardiovascular Pharmacology·María-Isabel CovasMontserrat Fitó

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.