Oliveros virus: a novel arenavirus from Argentina

Virology
M D BowenS T Nichol

Abstract

During the past few decades several newly recognized rodent-borne arenaviruses have been shown to be associated with severe hemorrhagic fever cases in South America. Changes in ecology and farming practices throughout the region have increased the concern over the potential public health threat posed by such emerging virus diseases. Oliveros (OLV) virus is a recently discovered arenavirus of the rodent Bolomys obscurus in Argentina. Genetic analysis of the small genomic RNA segment, which encodes the nucleocapsid protein and the envelope glycoproteins, shows that Oliveros is a novel, phylogenetically distinct member of the Arenaviridae family which differs in nucleotide sequence from the previously characterized members by approximately 35% or more. Despite this level of diversity, OLV virus possesses the same ambisense genome structure and many overall RNA and protein features in common with other arenaviruses. These data represent an important first step in the development of specific immunological and PCR diagnostic reagents to allow assessment of the prevalence and disease potential of this virus.

Citations

Sep 1, 2007·Vector Borne and Zoonotic Diseases·James N MillsPeter B Jahrling
Jul 11, 2000·Journal of Virology·M D BowenS T Nichol
Jan 25, 2013·Viruses·Juan C Zapata, Maria S Salvato
Feb 13, 2001·Biochemical and Biophysical Research Communications·R N CharrelC F Fulhorst
Jun 10, 2006·Infectious Disease Clinics of North America·Dennis J CleriJohn R Vernaleo
May 16, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Jorlan FernandesElba Regina Sampaio de Lemos
Dec 31, 2002·Virology·Angela M Archer, Rebeca Rico-Hesse
Jul 13, 2007·Virology·Maria N B CajimatCharles F Fulhorst
Jan 7, 1998·Journal of Virology·G KunoC B Cropp

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