Omega-3 fatty acids does not affect physical activity and body weight in primary school children - a double-blind randomized placebo-controlled trial

Scientific Reports
V SvenssonP Danielsson

Abstract

It was hypothesized that supplementation of omega-3 fatty acids could increase physical activity (PA) levels, where traditional interventions often fail. The aim of this double-blind, randomized, placebo-controlled trail was to evaluate the effects of 15-week administration of omega-3 fatty acids on objectively measured PA and relative body weight in 8-9 year-old children. The children were randomly assigned to supplementation of omega-3 fatty acids or placebo. Primary outcome was change in PA counts per minute (cpm), and secondly change in body mass index standard deviation score (BMI SDS). Covariance models were applied adjusting for age, gender, weight status, PA and intervention season. Compliance was controlled for by analyzing fatty acid composition in plasma. The intention to treat population consisted of 362 children (omega-3 n = 177, placebo n = 185). No significant effects of omega-3 fatty acids on PA or relative body weight were observed. In covariance models no effects were observed by gender, weight status or change in PA (all p > 0.05), but inactive children increased their PA more than children classified as active at baseline (p < 0.05).

References

Aug 31, 2004·International Journal of Epidemiology·Adrian G BarnettAnnette J Dobson
Apr 13, 2007·Acta Paediatrica·M GaremoB Strandvik
Apr 1, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Kevin C HarrisJennifer E Retallack
May 23, 2009·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J D Buckley, P R C Howe
Sep 4, 2009·Medicine and Science in Sports and Exercise·Gisela A NybergClaude Marcus
Jan 14, 2011·International Journal of Pediatric Obesity : IJPO : an Official Journal of the International Association for the Study of Obesity·T BurrowsM L Garg
Jan 22, 2011·Current Opinion in Clinical Nutrition and Metabolic Care·Sarah Egert, Peter Stehle
Oct 31, 2012·Archives of Pediatrics & Adolescent Medicine·Pernilla DanielssonClaude Marcus
Apr 23, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·R R PateS E Taverno Ross
Jun 27, 2013·The International Journal of Behavioral Nutrition and Physical Activity·Mirjam EkstedtClaude Marcus
Aug 21, 2013·Journal of the American College of Cardiology·Anita T CoteAngela M Devlin
Apr 8, 2014·Clinical Pediatrics·Sarah D de FerrantiStavroula K Osganian
Jun 4, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·N BenderM Egger
Oct 1, 2014·Nature Reviews. Endocrinology·Carl J LavieRichard V Milani
Jul 17, 2015·JPEN. Journal of Parenteral and Enteral Nutrition·Philip C Calder
Nov 28, 2015·Marine Drugs·Stewart JeromsonD Lee Hamilton

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Citations

May 1, 2019·International Journal of Molecular Sciences·Matilde AmatrudaElvira Verduci
Aug 1, 2021·Clinical Nutrition ESPEN·Felipe Mendes DelpinoBruna Gonçalves Cordeiro da Silva

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Clinical Trials Mentioned

NCT01087411

Software Mentioned

SPSS

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