PMID: 3772699Sep 1, 1986Paper

Omphalocele: a 25-year experience

Journal of Pediatric Surgery
S YazbeckA H Khan

Abstract

Between 1958 and 1983, 92 neonates with omphalocele were admitted to Ste-Justine Hospital. The male to female ratio was 3:2. Birth weight ranged from 1,450 to 5,100 g (mean 2,786 g). Associated anomalies, apart from malrotation, were present in 45%. They were cardiovascular (18.4%), vesico-intestinal fissure or bladder exstrophy (11.9%), Beckwith Wiedeman (6.5%), and chromosomal abnormalities (7.5%). Seven patients were not treated. Topical applications were used in seven cases (1 survivor). In 65%, primary closure was achieved; the mortality rate was 20% with a mean hospital stay of 17.5 days. Silastic was used in 12 cases with a mortality of 5/12 and a mean hospital stay of 82.1 days. The mean number of reductions was 6.7. Omphalocele rupture did not influence mortality. Prior to 1974 the mortality rate was 50%. Since 1974 it has decreased to 31.5%. The advent of total parenteral nutrition (TPN) was an important factor in decreasing the mortality. Prior to 1974, 23 patients survived, only one with a major associated anomaly (Fallot). After 1973, 35 survived, 13 having a major associated anomaly. Overall mortality was 9% when no other major malformations were present. A retrospective study of 92 cases of omphalocele over a 25-...Continue Reading

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Citations

Mar 1, 1996·Pediatric Surgery International·A ClausnerA Würfel
May 8, 2000·Indian Journal of Pediatrics·A Puri, M Bajpai
Nov 13, 2008·Pediatric Surgery International·P CharlesworthM McCullagh
Sep 3, 2010·Pediatric Surgery International·Polina FrolovMichael D Klein
Jun 18, 2011·Pediatric Surgery International·Chandrasen K SinhaA J Said
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Jul 29, 2009·Journal of Pediatric Surgery·T Mac BirdUNKNOWN National Birth Defects Prevention Study
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Aug 1, 1987·Journal of Pediatric Surgery·M Di LorenzoJ C Ducharme
Jun 1, 1995·Journal of Pediatric Surgery·J G NuchternE I Hatch
Feb 1, 1996·Journal of Pediatric Surgery·S KamataA Okada
Jun 1, 1996·Journal of Pediatric Surgery·D St-VilH Blanchard
Aug 1, 1996·Journal of Pediatric Surgery·D E TsakayannisC W Lillehei
Nov 1, 1990·Journal of Pediatric Surgery·S H Ein, A Bernstein
May 1, 1987·American Journal of Surgery·E I Hatch, R Baxter
Jul 26, 2006·Journal of Pediatric Surgery·Lorin LakasingKypros H Nicolaides
Mar 29, 2005·Journal of Pediatric Surgery·Ashok RijhwaniKypros Nicolaides
Dec 2, 2008·Journal of Pediatric Surgery·Hari R KumarAlan P Ladd
Dec 30, 2015·African Journal of Paediatric Surgery : AJPS·Almoutaz A Eltayeb, Mahmoud M Mostafa
Jan 1, 1995·Journal of Pediatric Surgery·I H Krasna
Jan 13, 1999·Prenatal Diagnosis·M D KilbyM Usher-Somers
Feb 24, 2006·Dermatology : International Journal for Clinical and Investigative Dermatology·Dong A TranMinh Tam Nguyen
Feb 1, 2021·Pediatric Surgery International·Arimatias RaitioIlkka Helenius
Mar 5, 2020·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·Arimatias RaitioIlkka Helenius
Mar 7, 2021·Children·Isabella N BielickiRaphael N Vuille-Dit-Bille

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