On a Fitzhugh-Nagumo type model for the pulse-like jasmonate defense response in plants

Mathematical Biosciences
S ChianggaT D Frank

Abstract

A mechanistic model of the Fitzhugh-Nagumo type is proposed for the pulse-like jasmonate response in plants. The model is composed of a bistable signaling pathway coupled to a negative feedback loop. The bistable signaling pathway describes a recently discovered positive feedback loop involving jasmonate and the MYC2 transcription factor regulating promoter activity during plant defense. The negative feedback loop is assumed to reflect a second jasmonate-dependent signaling pathway that is also used for ethylene signaling. The impact of the negative feedback loop is to destroy the high-level jasmonate fixed-point of the bistable jasmonate/MYC2 module. As a result, the high-level state becomes a ghost attractor and the jasmonate defense response becomes pulse-like.

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Citations

Mar 15, 2018·Annual Review of Plant Biology·Gregg A HoweAbraham J Koo

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