On-going and reflex synaptic events in rat superior cervical ganglion cells

The Journal of Physiology
E M McLachlanJ Jamieson

Abstract

1. Synaptic events evoked by brief noxious cutaneous stimuli were recorded in sympathetic neurones in the superior cervical ganglion of anaesthetized rats. 2. On-going excitatory synaptic potentials (ESPs) and/or action potentials (APs) were recorded in 69% of neurones at mean frequencies that varied from 0.01 to 6.3 Hz in different cells. From histograms of ESP amplitude during membrane hyperpolarization, it appears that most cells received one (52%), or two or more (36%), suprathreshold inputs and several subthreshold inputs with overlapping amplitudes. 3. Pinching the skin for 1-3 s evoked either a brief burst of synaptic events (lasting about 300 ms) preceding a few seconds of inhibition (burst-inhibitory (BI) neurones), or simply an excitation (excitatory (E) neurones), or no response (O neurones). In 60% of BI neurones, a second burst occurred after the end of the pinch. 4. BI neurones had a higher frequency of on-going synaptic activity (2.9 +/- 0.5 Hz, n = 15) than E neurones (0.2 +/- 0.1 Hz, n = 5) or O (0.2 +/- 0.1 Hz, n = 5) neurones. Most neurones with two or more suprathreshold inputs were BI neurones. In 20% of neurones (all BI with high rates of synaptic activity), several other inputs had ESPs with amplitudes cl...Continue Reading

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Citations

Feb 1, 2007·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Elspeth M McLachlan
Nov 1, 2007·Neir̆ofiziologiia = Neurophysiology·J P Horn, P H M Kullmann
Oct 7, 2000·Autonomic Neuroscience : Basic & Clinical·T BartschH J Häbler
Jul 22, 1998·Journal of the Autonomic Nervous System·K Kukuła, P J Szulczyk
Jul 28, 2001·Autonomic Neuroscience : Basic & Clinical·T NishiyamaT Mano
Mar 2, 2002·Autonomic Neuroscience : Basic & Clinical·Vaughan G MacefieldB Gunnar Wallin
Feb 15, 2014·Autonomic Neuroscience : Basic & Clinical·Wilfrid Jänig
Oct 19, 2011·The Journal of Physiology·Robin M McAllenAnthony E Pickering
Mar 24, 2010·The Journal of Physiology·Bradford BrattonRobin McAllen
Aug 16, 2008·The Journal of Physiology·Anna P Perez-GonzalezArtur Llobet
Jan 29, 2010·Autonomic Neuroscience : Basic & Clinical·Paul H M Kullmann, John P Horn
Jul 16, 2016·The Journal of Physiology·Wilfrid Jänig
Apr 28, 2005·Clinical and Experimental Pharmacology & Physiology·Robin M McAllenBradford O Bratton
Sep 24, 2005·Journal of Neurophysiology·Chen Li, John P Horn
May 13, 2003·Journal of Neurophysiology·John JamiesonElspeth M McLachlan
Jan 25, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Priscila A CassagliaAdrian M Walker
Mar 1, 2003·Acta Physiologica Scandinavica·Ian L GibbinsJudy L Morris
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Sep 14, 1999·The American Journal of Physiology·H Izumi
Nov 17, 2017·Journal of Neurophysiology·Vaughan G Macefield, B Gunnar Wallin

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