On issues of confidence in determining the time constant for oxygen uptake kinetics

British Journal of Sports Medicine
G H MarkovitzC B Cooper

Abstract

TauVO(2 )at the onset of constant work rate (CWR) exercise is a variable of aerobic fitness that shortens with physical training and lengthens with cardiopulmonary disease. Determination of tauVO(2) with sufficiently high confidence has typically required multiple exercise transitions limiting its clinical application. To design a protocol to determine tauVO(2) reliably but simply. On each of three days, five healthy men performed two CWR tests on a cycle ergometer below the metabolic threshold (VO(2)theta) for blood lactate accumulation as determined by gas exchange measurements followed by an incremental work rate (IWR) test. TauVO(2) was determined (a) from the on-transit (on-tauVO(2)) and off-transit (off-tauVO(2)) of six CWR tests both individually and superimposed, using non-linear regression with a monoexponential model, and (b) by geometric analysis of the IWR tests (ramp-tauVO(2)). Group means (SD) were: VO(2)max 3.84 (0.44) litres/min, VO(2)theta 1.88 (0.23) litres/min, steady state exercise VO(2) 1.67 (0.07) litres/min, on-tauVO(2) 38.0 (5.3) seconds, off-tauVO(2) 39.0 (4.3) seconds, and ramp-tauVO(2) 60.8 (15.4) seconds. On-tauVO(2) correlated with off-tauVO(2) (r = 0.87), VO(2)max (r = -0.73), and VO(2)theta (r = 0...Continue Reading

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Citations

Aug 22, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·C R PotterV B Unnithan
Feb 12, 2014·Thyroid : Official Journal of the American Thyroid Association·Francisco Zacaron WerneckMário Vaisman
Dec 25, 2015·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Jan BooneJan Bourgois
Mar 1, 2012·Respiratory Physiology & Neurobiology·Aurélien BringardStéphane Perrey
Dec 31, 2014·European Journal of Applied Physiology·J RibeiroR F Fernandes
Dec 17, 2014·Respiratory Physiology & Neurobiology·Paulo de Tarso MüllerJ Alberto Neder
Jan 10, 2018·Medicine and Science in Sports and Exercise·Kevin CaenJan Boone
Jan 3, 2019·Medicine and Science in Sports and Exercise·Danilo IannettaDaniel A Keir
Nov 14, 2015·Journal of Applied Physiology·Samuel L WilcoxThomas J Barstow
Jul 14, 2017·Journal of Neuroengineering and Rehabilitation·Philippe MalcolmConor J Walsh
Dec 17, 2020·Frontiers in Bioengineering and Biotechnology·Marleny M AronesBenjamin J Fregly

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