On-line assessment of delivered dialysis dose

Kidney International
S Di FilippoF Locatelli

Abstract

The adequacy of the delivered dialysis dose is essential to prevent patient morbidity and mortality. The determination of effective ionic dialysance (D) is easy, non-invasive and inexpensive, and its use instead of effective urea clearance (K) in kinetically determining apparent" urea distribution volume (Vt) is likely to lead to a correct Kt/V, even though the Vt value may be incorrect. The aim of this study was to test the possibility of using the measurement of D to monitor Kt/V on-line during each dialysis treatment. Forty-four patients were dialyzed using a monitor equipped with specially designed "Diascan Module" (COT; Hospal) that measures effective D by means of a single conductivity probe. Vt was calculated according to the SPVV three BUN method urea kinetic model using D instead of K values. One month later, Kt/V was calculated as Dt/V, using actual D and T values and the predetermined Vt values updated for the current final body wt. Both the Dt/V and Kt/V determined according to the Smye and Daugirdas methods were compared with the Kt/V determined using the SPVV kinetic model (Kt/Veq) The Kt/V values calculated using ionic dialysance and predetermined Vt were approximately equivalent to those of Kt/Veq (1.14 +/- 0.16...Continue Reading

References

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Citations

Jan 6, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Francesco LocatelliPietro Zucchelli
Aug 14, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Elizabeth J LindleyEric J Will
Nov 6, 2010·Expert Review of Medical Devices·Hans-Dietrich Polaschegg
Mar 7, 2006·Kidney International·S Di FilippoF Locatelli
Jun 24, 2010·Néphrologie & thérapeutique·Alain FicheuxAngel Argilés
Sep 30, 2005·Hemodialysis International·Lucile MercadalThierry Petitclerc
Oct 25, 2016·Seminars in Dialysis·Shubha Ananthakrishnan, Thomas A Depner
May 1, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·U KuhlmannH Lange
Aug 28, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J P KoomanK M Leunissen
Sep 26, 2002·The International Journal of Artificial Organs·I FridolinL G Lindberg
Oct 18, 2003·Current Opinion in Nephrology and Hypertension·Stewart H Lambie, Christopher W McIntyre
Nov 10, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·F LocatelliD Spotti
May 2, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Fredrik UhlinMartin Magnusson
May 6, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Francisco MaduellJosep M Campistol

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