On mixed electron-photon radiation therapy optimization using the column generation approach

Medical Physics
Marc-André RenaudJan Seuntjens

Abstract

Despite considerable increase in the number of degrees of freedom handled by recent radiotherapy optimisation algorithms, treatments are still typically delivered using a single modality. Column generation is an iterative method for solving large optimisation problems. It is well suited for mixed-modality (e.g., photon-electron) optimisation as the aperture shaping and modality selection problem can be solved rapidly, and the performance of the algorithm scales favourably with increasing degrees of freedom. We demonstrate that the column generation method applied to mixed photon-electron planning can efficiently generate treatment plans and investigate its behaviour under different aperture addition schemes. Column generation was applied to the problem of mixed-modality treatment planning for a chest wall case and a leg sarcoma case. 6 MV beamlets (100 cm SAD) were generated for the photon components along with 5 energies for electron beamlets (6, 9, 12, 16 and 20 MeV), simulated as shortened-SAD (80 cm) beams collimated with a photon MLC. For the chest wall case, IMRT-only, modulated electron radiation therapy (MERT)-only, and mixed electron-photon (MBRT) treatment plans were created using the same planning criteria. For the s...Continue Reading

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Citations

Dec 8, 2017·Physics in Medicine and Biology·S MuellerP Manser
Aug 29, 2018·Medical Physics·Dylan Y BreitkreutzMagdalena Bazalova-Carter
Jan 11, 2019·Medical Physics·Marc-André RenaudJan Seuntjens
Feb 23, 2019·Physics in Medicine and Biology·Mehdi MahnamLouis-Martin Rousseau
Mar 28, 2020·Medical Physics·Joel MullinsJan Seuntjens
Mar 22, 2020·Medical Physics·Joel MullinsJan Seuntjens
May 16, 2020·Physics in Medicine and Biology·R KuengP Manser
Feb 22, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Shadab MominRao F Khan
Sep 20, 2020·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·R KuengM K Fix
Nov 1, 2019·Biomedical Physics & Engineering Express·Dylan Yamabe BreitkreutzMagdalena Bazalova-Carter
Jul 6, 2021·Medical Physics·Veng Jean HengMarc-André Renaud
Oct 1, 2021·Physics in Medicine and Biology·Peyman KafaeiLouis-Martin Rousseau

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