On-surface chemical reactions characterised by ultra-high resolution scanning probe microscopy

Chemical Society Reviews
Adam SweetmanAlex Saywell

Abstract

In the last decade it has become possible to resolve the geometric structure of organic molecules with intramolecular resolution using high resolution scanning probe microscopy (SPM), and specifically using the subset of SPM known as noncontact atomic force microscopy (ncAFM). In world leading groups it has become routine not only to perform sub-molecular imaging of the chemical, electronic, and electrostatic properties of single molecules, but also to use this technique to track complex on-surface chemical reactions, investigate novel reaction products, and even synthesise new molecular structures one bond at a time. These developments represent the cutting edge of characterisation at the single chemical bond level, and have revolutionised our understanding of surface-based chemical processes.

References

Mar 3, 2007·Nature·Yoshiaki SugimotoOscar Custance
Apr 14, 2007·Annual Review of Physical Chemistry·Johannes V Barth
Jul 26, 2008·Nature Nanotechnology·Leonhard GrillStefan Hecht
Jul 24, 2010·Nature·Jinming CaiRoman Fasel
Sep 18, 2012·Science·Leo GrossGerhard Meyer
Oct 16, 2012·Nature Nanotechnology·Matthias KochLeonhard Grill
Jun 1, 2013·Science·Dimas G de OteyzaFelix R Fischer
Jun 13, 2013·Nature Communications·Joost van der LitIngmar Swart
May 31, 2014·Nature Communications·A M SweetmanP Moriarty
Aug 29, 2014·Physical Review Letters·Bruno SchulerLeo Gross
Nov 15, 2014·Physical Review Letters·Sampsa K HämäläinenIngmar Swart
May 13, 2015·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Robert Lindner, Angelika Kühnle
Jul 15, 2015·Journal of the American Chemical Society·Bruno SchulerLeo Gross
Jul 16, 2015·Nano Letters·Thomas DienelOliver Gröning
Feb 4, 2016·Nano Letters·Michael EllnerRubén Peréz
Feb 20, 2016·Nature Chemistry·Bruno SchulerLeo Gross
Mar 25, 2016·Nature·Pascal RuffieuxRoman Fasel
May 14, 2016·Nature Communications·Shigeki KawaiErnst Meyer
Aug 11, 2016·ACS Nano·Nadine J van der HeijdenIngmar Swart
Dec 21, 2016·Nature Chemistry·Yuanqin HeJohannes V Barth
Apr 1, 2017·Nature Communications·Meizhuang LiuDingyong Zhong
Feb 28, 2018·Angewandte Chemie·Leo GrossGerhard Meyer
Apr 18, 2018·Science Advances·Shigeki KawaiAdam S Foster
Dec 14, 2018·Nature Nanotechnology·John E SaderFranz J Giessibl
Feb 3, 2019·The Review of Scientific Instruments·Franz J Giessibl

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Citations

Jan 7, 2021·Chemical Society Reviews·Brent DaelemansSteven De Feyter
Apr 24, 2021·Chemical Communications : Chem Comm·Kaleb A Reid, David C Powers
Jul 11, 2021·The Review of Scientific Instruments·Jonas HeggemannPhilipp Rahe
Oct 16, 2021·Scientific Reports·Abigail Bellamy-CarterAlex Saywell
Jan 28, 2022·Nature Communications·Kristjan EimreCarlo A Pignedoli

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Methods Mentioned

BETA
scanning
atomic force microscopy
X-ray
electron diffraction
nuclear magnetic resonance
NMR
AFM
dynamic

Software Mentioned

qPlus ncAFM
qPlus
ncAFM
SPM

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