On the Accurate Determination of Shock Wave Time-Pressure Profile in the Experimental Models of Blast-Induced Neurotrauma

Frontiers in Neurology
Maciej SkotakNamas Chandra

Abstract

Measurement issues leading to the acquisition of artifact-free shock wave pressure-time profiles are discussed. We address the importance of in-house sensor calibration and data acquisition sampling rate. Sensor calibration takes into account possible differences between calibration methodology in a manufacturing facility, and those used in the specific laboratory. We found in-house calibration factors of brand new sensors differ by less than 10% from their manufacturer supplied data. Larger differences were noticeable for sensors that have been used for hundreds of experiments and were as high as 30% for sensors close to the end of their useful lifetime. These observations were despite the fact that typical overpressures in our experiments do not exceed 50 psi for sensors that are rated at 1,000 psi maximum pressure. We demonstrate that sampling rate of 1,000 kHz is necessary to capture the correct rise time values, but there were no statistically significant differences between peak overpressure and impulse values for low-intensity shock waves (Mach number <2) at lower rates. We discuss two sources of experimental errors originating from mechanical vibration and electromagnetic interference on the quality of a waveform record...Continue Reading

References

Jul 27, 1999·The Journal of Trauma·I CernakM Jevtic
Jul 27, 1999·The Journal of Trauma·R J IrwinD W Tuggle
Apr 1, 2005·The New England Journal of Medicine·Ralph G DePalmaMichael J Hodgson
Feb 1, 2008·The New England Journal of Medicine·Charles W HogeCarl A Castro
Jan 17, 2009·Journal of Neurotrauma·Annette SäljöAnders Hamberger
Mar 24, 2009·The Mount Sinai Journal of Medicine, New York·Gregory A Elder, Adrian Cristian
May 8, 2010·NeuroRehabilitation·David F Moore, Michael S Jaffee
Nov 19, 2010·Journal of Neurotrauma·Dexter V ReneerJames W Geddes
Dec 7, 2010·Journal of Neuroscience Methods·Mikulas ChavkoRichard M McCarron
Apr 1, 2011·Journal of Neurotrauma·Robert H GarmanPatrick M Kochanek
Sep 29, 2011·Experimental Neurology·Vardit RubovitchChaim G Pick
May 9, 2012·The Review of Scientific Instruments·Amy C CourtneyMichael W Courtney
Apr 10, 2013·Annals of Biomedical Engineering·Stewart YeohKenneth L Monson
Mar 3, 2015·Frontiers in Neurology·Anna P MillerAleksandra Glavaski-Joksimovic

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