PMID: 9432537Jan 1, 1997Paper

On the choice of pharmacotherapy for the treatment of arterial hypertension in elderly patients with diabetes mellitus

Klinicheskaia meditsina
V I Burtsev, V A Kochnova

Abstract

107 male patients with diabetes mellitus type II (DM) combined with hypertension aged 62 to 76 years were divided into 5 groups comparable by DM but different by characteristics of hypertension, ischemic heart disease or other associated diseases the presence of which determined the choice of one or another drugs against hypertension. These drugs belonging to 5 groups (calcium antagonists, inhibitors of angiotensin converting enzymes, beta-blockers, alpha-blockers, agonists of imidasoline receptors) were compared in monotherapy and combined therapy for hypotensive activity and safety. It was found that monotherapy with corinfar, capoten, and cint had a potent hypotensive effect, atenolol and prasosin had moderate hypotensive efficacy and caused side effects more frequently. In differentiated use of the above drugs negative effects on associated diseases did not occur.

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.