On the determination of underivatised fatty alcohol ethoxylates by electrospray ionisation-mass spectrometry

Journal of Chromatography. a
Virginia Bernabé-ZafónGuillermo Ramis-Ramos

Abstract

The oligomers of fatty alcohol ethoxylates (FAEs) exhibit large sensitivity differences in mass spectrometry with electrospray ionisation (ESI-MS) and atmospheric pressure chemical ionization (APCI). Standards of the oligomers from m=1 to 7 ethylene oxide units (EOs) and linear alkyl chains from n=10 to 18 carbon atoms were infused to examine the relative sensitivities or response factors in several media. The response factors of the [M+H]+ and [M+Na]+ peaks in 9:1 acetonitrile/water and methanol/water media containing acid buffers increased following irregular patterns when n and m increased. In methanol/water the response factors depended on the parity of m, being larger than the average trend for the oligomers with an even value of m with respect to those having an odd value. This was attributed to the presence of an uncompensated C-O-C or C-O-H dipole in the former oligomers. The advantages of using ESI over APCI and of measuring the [M+H]+ peaks in an acid methanol/water medium containing 0.1 M HCl are discussed. The advantages and limitations of using models of the response factors to evaluate oligomer concentrations with a reduced set of selected standards are examined. The determination of underivatised FAEs using acid ...Continue Reading

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Citations

Apr 27, 2013·Talanta·Juan Manuel Traverso-SotoEduardo González-Mazo
Feb 12, 2013·Ecotoxicology and Environmental Safety·Dorota NowickaZenon Lukaszewski
Jan 20, 2011·Mass Spectrometry Reviews·P TerrierW Buchmann
Feb 16, 2010·Journal of Separation Science·Anna Micó-TormosGuillermo Ramis-Ramos
Jun 17, 2010·Rapid Communications in Mass Spectrometry : RCM·Miriam Beneito-CambraGuillermo Ramis-Ramos
Jul 25, 2015·Analytical and Bioanalytical Chemistry·Eduard DeibelOliver J Schmitz
Jan 31, 2007·Journal of Mass Spectrometry : JMS

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