On the efficiency and accuracy of the single equivalent moving dipole method to identify sites of cardiac electrical activation

Medical & Biological Engineering & Computing
Kwanghyun Sohn, Antonis A Armoundas

Abstract

We have proposed an algorithm to guide radiofrequency catheter ablation procedures. This algorithm employs the single equivalent moving dipole (SEMD) to model cardiac electrical activity. The aim of this study is to investigate the optimal time instant during the cardiac cycle as well as the number of beats needed to accurately estimate the location of a pacing site. We have evaluated this algorithm by pacing the ventricular epicardial surface and inversely estimating the locations of pacing electrodes from the recorded body surface potentials. Two pacing electrode arrays were sutured on the right and left ventricular epicardial surfaces in swine. The hearts were paced by the electrodes sequentially at multiple rates (120-220 bpm), and body surface ECG signals from 64 leads were recorded for the SEMD estimation. We evaluated the combined error of the estimated interelectrode distance and SEMD direction at each time instant during the cardiac cycle, and found the error was minimum when the normalized root mean square (RMS n ) value of body surface ECG signals reached 15 % of its maximum value. The beat-to-beat variation of the SEMD locations was significantly reduced (p < 0.001) when estimated at 15 % RMS n compared to the earli...Continue Reading

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Citations

Dec 15, 2017·Environmental Health : a Global Access Science Source·Ben K GreenfieldThomas E McKone
Feb 25, 2021·Journal of Cardiovascular Electrophysiology·Wener LvKichang Lee

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