On the information content of the genetic code

Bio Systems
T AlvagerJ Westgard


In living organisms 20 amino acids along with the terminator value(s) are encoded by 64 codons giving a degeneracy of the codons as described by the genetic code. A basic theoretical problem of genetic codes is to explain the particular distribution of degeneracies of partitions involved in the codes. In this work the degeneracy problem is considered in the framework of information theory. It is shown by direct numerical evaluation of a certain degeneracy information function associated with the genetic code that the degeneracy of the codes is observed to be related to the optimization of this function.


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Aug 1, 1966·Journal of Molecular Biology·F H Crick
Apr 1, 1981·Scientific American·M EigenR Winkler-Oswatitsch
Mar 21, 1983·Journal of Theoretical Biology·G W Rowe, L E Trainor
Jan 1, 1983·Journal of Molecular Evolution·T H Jukes

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