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On the mechanism of ketogenesis and its control. Purification, kinetic mechanism and regulation of different forms of mitochondrial acetoacetyl-CoA thiolases from ox liver

European Journal of Biochemistry

Nov 15, 1975

Walter HuthW Seubert

PMID: 1256

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Abstract

1. Two mitochondrial forms of acetoacetyl-CoA thiolases designated as enzyme A and enzyme B were crystallized from ox liver. They could be shown to be homogenous by polyacrylamide gel electrophoresis. 2. In direction of acetoacetyl-CoA cleavage enzyme A shows a double competitive substr...read more

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Enzymes, antithrombotic
Enzymes, peripheral vasodilators
3-hydroxybutyryl-coenzyme A
Acetyl-CoA C-Acetyltransferase
Mitochondria, Liver
NADH
Alloenzymes
Acetyl Coenzyme A
Enzymes, hematological
Polymorphism, Crystallization
Paper Details
References
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    • References13
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  • On the mechanism of ketogenesis and its control. Purification, kinetic mechanism and regulation of different forms of mitochondrial acetoacetyl-CoA thiolases from ox liver

    European Journal of Biochemistry

    Nov 15, 1975

    Walter HuthW Seubert

    PMID: 1256

    DOI:

    Abstract

    1. Two mitochondrial forms of acetoacetyl-CoA thiolases designated as enzyme A and enzyme B were crystallized from ox liver. They could be shown to be homogenous by polyacrylamide gel electrophoresis. 2. In direction of acetoacetyl-CoA cleavage enzyme A shows a double competitive substr...read more

    Mentioned in this Paper

    Enzymes, antithrombotic
    Enzymes, peripheral vasodilators
    3-hydroxybutyryl-coenzyme A
    Acetyl-CoA C-Acetyltransferase
    Mitochondria, Liver

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    Paper Details
    References
    • References13
    • Citations12
    • References13
    • Citations12
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