On the origin of species: Factors shaping the establishment of infant's gut microbiota

Birth Defects Research. Part C, Embryo Today : Reviews
Niels van BestJohn Penders

Abstract

The human gut microbiota is a complex and dynamic ecosystem, which naturally lives in a symbiotic relationship with the host. Perturbations of the microbial composition (dysbiosis) and reduced diversity may promote disease susceptibility and recurrence. In contrast to the mature intestinal microbiota of healthy adults, which appears relatively stable over time, the infant's microbiome only establishes and matures during the first years of life. In this respect, early childhood seems to represent a crucial age-window in disease prevention, since microbial diversification and maturation of the microbiome primarily occurs during this period of life. A better understanding of ecological processes and pioneer consortia in microbial development is crucial, in order to support the development of a beneficial microbiota. Various deterministic and stochastic aspects seem to shape the microbiome in early life, including maternal, environmental, and host factors. Here, we review the current understanding of the origin of pioneer bacteria and the evolutionary factors that influence the development of the gut microbiota in infants. In addition, future perspectives, including manipulating and promoting the succession of initial bacteria duri...Continue Reading

References

May 16, 2001·Science·L V Hooper, J I Gordon
Jan 5, 2002·Applied and Environmental Microbiology·Christine F FavierAntoon D L Akkermans
Mar 26, 2003·Annual Review of Nutrition·Matthew D GriffinRajiv Kumar
Aug 13, 2003·Journal of Applied Microbiology·M P Heikkilä, P E J Saris
Jan 13, 2004·Clinics in Perinatology·Robert L Goldenberg, Jennifer Flatow Culhane
Jun 3, 2004·Nature Reviews. Immunology·Andrew J Macpherson, Nicola L Harris
Jul 6, 2006·Trends in Ecology & Evolution·Les DethlefsenDavid A Relman
Aug 3, 2006·Pediatrics·John PendersEllen E Stobberingh
Dec 22, 2006·Nature·Peter J TurnbaughJeffrey I Gordon
Mar 3, 2007·Pediatrics·Pablo F PerezAnne Donnet-Hughes
Jun 28, 2007·PLoS Biology·Chana PalmerPatrick O Brown
Jul 3, 2007·The Journal of Allergy and Clinical Immunology·Ingegerd AdlerberthAgnes E Wold
Oct 19, 2007·Nature·Peter J TurnbaughJeffrey I Gordon
Feb 19, 2008·Research in Microbiology·Esther JiménezJuan M Rodríguez
Mar 11, 2008·The American Journal of Clinical Nutrition·Marko KalliomäkiErika Isolauri
Aug 30, 2008·PloS One·Zaruhi A KhachatryanRustam I Aminov
Dec 2, 2008·Nature·Peter J TurnbaughJeffrey I Gordon
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Tanja Petnicki-OcwiejaKoichi S Kobayashi
Oct 27, 2009·Nature Immunology·Nita H SalzmanNicolaas A Bos
May 19, 2010·Journal of Pediatric Gastroenterology and Nutrition·Matteo FallaniUNKNOWN Other Members of the INFABIO Team
Jun 23, 2010·Proceedings of the National Academy of Sciences of the United States of America·Maria G Dominguez-BelloRob Knight
Jul 30, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jeremy E KoenigRuth E Ley
Aug 4, 2010·Proceedings of the National Academy of Sciences of the United States of America·Angela M ZivkovicDavid A Mills
Aug 4, 2010·Proceedings of the National Academy of Sciences of the United States of America·Carlotta De FilippoPaolo Lionetti
Sep 18, 2010·Proceedings of the National Academy of Sciences of the United States of America·Les Dethlefsen, David A Relman
Dec 15, 2010·Acta Paediatrica·F SavinoV Tullio
Jan 25, 2011·Pediatric Research·Adora C Okogbule-WonodiRose Marie Viscardi
Mar 10, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T A AjslevT Jess
Mar 23, 2011·The Journal of Allergy and Clinical Immunology·Ngoc P LyJuan C Celedón
Nov 9, 2011·Pediatrics·Adam L HershSamir S Shah
Nov 10, 2011·Proceedings of the National Academy of Sciences of the United States of America·Philipp RauschJohn F Baines
Dec 6, 2011·Seminars in Fetal & Neonatal Medicine·Daniel B DiGiulio
Jan 10, 2012·Journal of Pediatric Gastroenterology and Nutrition·Łukasz GrześkowiakSeppo Salminen
Jun 16, 2012·Nature·Tanya YatsunenkoJeffrey I Gordon
Jul 28, 2012·The American Journal of Clinical Nutrition·Raul Cabrera-RubioAlex Mira
Aug 22, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·L TrasandeM J Blaser

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Citations

Apr 19, 2016·Best Practice & Research. Clinical Gastroenterology·Daisy M A E Jonkers
Apr 14, 2016·Trends in Immunology·Oliver PabstMathias Hornef
Jan 26, 2017·Mucosal Immunology·M Hornef, J Penders
Sep 9, 2017·The Pediatric Infectious Disease Journal·Nikolas ChristensenSteffen Husby
Jun 7, 2018·Critical Reviews in Food Science and Nutrition·Xiaoli ZhouZongjie Li
May 31, 2018·Current Opinion in Infectious Diseases·Geeta SoodJeanne S Sheffield
Nov 18, 2016·The Journal of Experimental Biology·Kevin D Kohl, Hannah V Carey
Aug 24, 2018·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Paul Bryde AxelssonEllen Christine Leth Løkkegaard
Oct 3, 2018·Epidemiology·Paul Bryde AxelssonEllen Christine Leth Løkkegaard
Mar 28, 2017·Frontiers in Microbiology·Jeroen A A van de PolJohn Penders
Nov 20, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M Kumari, A L Kozyrskyj
Mar 16, 2019·Frontiers in Pediatrics·Lieke W J van den ElsenValerie Verhasselt
Apr 28, 2017·Pediatric Obesity·R W WalkerR J F Loos
Jul 25, 2020·Nature Communications·N van BestM W Hornef
Jul 16, 2020·Sleep Medicine Reviews·Brittany A MatenchukAnita L Kozyrskyj
Sep 12, 2017·Brain, Behavior, and Immunity·Alexandra Castillo-RuizNancy G Forger
May 26, 2021·ELife·Philipp HennekeMathias Hornef
Aug 10, 2021·Brain, Behavior, and Immunity·Fabian StreitRobert Yolken
Oct 1, 2021·Journal of Proteome Research·Liene BervoetsJohn Penders

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