On the phenomenology of lethal applications of insulin

Forensic Science International : Synergy
G Kernbach-Wighton, Klaus Püschel

Abstract

This study deals with the postmortem findings in cases of lethal hypoglycaemia due to injections of insulin. In 12 cases (four female; eight male; mean age 42 years) the following aspects were evaluated retrospectively: circumstances of life, scene of death, pathomorphological findings and postmortem biochemistry on cerebrospinal fluid, vitreous humour, blood, and urine (levels of glucose, lactate, hemoglobin A1C and insulin). Furthermore, analyses of ethanol in blood and urine as well as toxicological and histological examinations were performed. Unexpectedly, the dead persons rarely represented diabetics, relatives of diabetics, or medical personnel. It is concluded, that the diagnosis of fatal hypoglycaemia can only be established by a synopsis of postmortem biochemistry, pathomorphological alterations and anamnesis. Besides, this diagnosis must always be made "per exclusionem".

References

May 27, 1977·Zeitschrift für Rechtsmedizin. Journal of legal medicine·C F Hänsch, G De Roy
Aug 19, 1976·The New England Journal of Medicine·R J KoenigA Cerami
May 1, 1985·The British Journal of Psychiatry : the Journal of Mental Science·D James, K Hawton
Sep 1, 1968·The American Journal of the Medical Sciences·D P Henry, R Bressler
Jan 1, 1983·Journal - Forensic Science Society·S M Fletcher
Jul 23, 1983·British Medical Journal·H GinJ Aubertin
Jul 28, 1984·British Medical Journal·J A CritchleyA Gordon
Aug 7, 1982·British Medical Journal·I W Campbell, J G Ratcliffe
May 1, 1982·Forensic Science International : Synergy·H Sippel, M Möttönen
Apr 1, 1994·Diabetic Medicine : a Journal of the British Diabetic Association·P FaschingA N Laggner
Sep 1, 1993·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·D F MooreG N Volans
Feb 1, 1993·Annals of Emergency Medicine·R J RobergeT R Delbridge
Sep 1, 1959·Archives of Ophthalmology·H N NAUMANN

Citations

Sep 30, 2010·International Journal of Legal Medicine·Cornelius HessBurkhard Madea
Sep 29, 2011·International Journal of Legal Medicine·Cristian Palmiere, Patrice Mangin
Sep 9, 2000·Forensic Science International : Synergy·M JungeK Püschel
Nov 1, 2000·Forensic Science International : Synergy·H IwaseT Takatori
Nov 1, 2000·Forensic Science International : Synergy·G Kernbach-WightonKlaus Püschel
Sep 29, 1999·Endocrinology and Metabolism Clinics of North America·V Marks, J D Teale
Sep 16, 2000·The American Journal of Forensic Medicine and Pathology·D C Winston
Sep 25, 2015·Journal of Forensic Sciences·Nick SunderlandCarol K Lee
Nov 22, 2011·Drug Testing and Analysis·Mario ThevisIlkka Ojanperä
Feb 3, 2015·Drug Testing and Analysis·Cristian PalmiereDaniel Bardy

Related Concepts

Legal Medicine Discipline
Reactive Hypoglycemia
Insulin B Chain
Liver
Livor Mortis
Retrospective Studies
Suicide

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