On the predictability of infectious disease outbreaks

Nature Communications
Samuel V Scarpino, Giovanni Petri

Abstract

Infectious disease outbreaks recapitulate biology: they emerge from the multi-level interaction of hosts, pathogens, and environment. Therefore, outbreak forecasting requires an integrative approach to modeling. While specific components of outbreaks are predictable, it remains unclear whether fundamental limits to outbreak prediction exist. Here, adopting permutation entropy as a model independent measure of predictability, we study the predictability of a diverse collection of outbreaks and identify a fundamental entropy barrier for disease time series forecasting. However, this barrier is often beyond the time scale of single outbreaks, implying prediction is likely to succeed. We show that forecast horizons vary by disease and that both shifting model structures and social network heterogeneity are likely mechanisms for differences in predictability. Our results highlight the importance of embracing dynamic modeling approaches, suggest challenges for performing model selection across long time series, and may relate more broadly to the predictability of complex adaptive systems.

References

Aug 24, 1987·Physical Review Letters·J D Farmer, J J Sidorowich
Sep 21, 2000·Advances in Parasitology·M F MyersS I Hay
May 15, 2002·Physical Review Letters·Christoph Bandt, Bernd Pompe
May 27, 2003·Science·Chris Dye, Nigel Gay
Oct 13, 2004·Proceedings of the National Academy of Sciences of the United States of America·L HufnagelT Geisel
Oct 23, 2004·Journal of Theoretical Biology·Lauren Ancel MeyersRobert C Brunham
Aug 2, 2005·Proceedings of the National Academy of Sciences of the United States of America·Duncan J WattsPeter S Dodds
Feb 8, 2006·Proceedings of the National Academy of Sciences of the United States of America·Vittoria ColizzaAlessandro Vespignani
Oct 27, 2007·Journal of Applied Physiology·D J CollierC B Wolff
Jun 19, 2012·Scientific Reports·Michael SzellVito Latora
Jun 29, 2012·Scientific Reports·N PerraA Vespignani
Dec 12, 2012·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·L ZuninoO A Rosso
Mar 19, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Bilal FadlallahJosé Príncipe
Jul 5, 2013·PloS One·Elaine O NsoesieMadhav V Marathe
Nov 29, 2013·The New England Journal of Medicine·Willem G van PanhuisDonald S Burke
Dec 5, 2013·Nature Communications·Jeffrey ShamanMarc Lipsitch
Dec 11, 2014·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Joshua GarlandElizabeth Bradley
Dec 17, 2014·Proceedings of the National Academy of Sciences of the United States of America·Eric T LofgrenStephen Eubank
Sep 1, 2015·PLoS Computational Biology·Logan C BrooksRoni Rosenfeld
Sep 10, 2015·Proceedings of the National Academy of Sciences of the United States of America·Amy WesolowskiCaroline O Buckee
Jun 16, 2016·PLoS Neglected Tropical Diseases·Nicholas G ReichJustin Lessler
Jul 28, 2016·BMC Infectious Diseases·Matthew BiggerstaffUNKNOWN Influenza Forecasting Contest Working Group
Aug 28, 2016·Trends in Ecology & Evolution·Sylvain GandonBryan T Grenfell
Nov 1, 2016·Journal of the Royal Society, Interface·Christopher J DibbleJohn M Drake
Mar 4, 2017·Epidemics·Srinivasan VenkatramananMadhav Marathe
Apr 22, 2017·Physical Review Letters·Antonio Politi
Aug 24, 2017·The Journal of Infectious Diseases·Shweta BansalCécile Viboud
Sep 7, 2017·Theoretical Biology & Medical Modelling·Paige B MillerJohn M Drake
Sep 30, 2017·Epidemics·Cécile ViboudUNKNOWN RAPIDD Ebola Forecasting Challenge group
Feb 21, 2018·PLoS Computational Biology·Evan L Ray, Nicholas G Reich
Mar 30, 2018·Science Translational Medicine·Matthieu Domenech de CellèsPejman Rohani
Jun 9, 2018·Nature·Edward C HolmesKristian G Andersen
Jun 9, 2018·PLoS Computational Biology·Tobias S BrettPejman Rohani
Jul 26, 2018·Nature·Caitlin M Rivers, Samuel V Scarpino
Aug 26, 2018·Scientific Reports·Pietro ColettiVittoria Colizza
Oct 6, 2018·Science·Benjamin D DalzielBryan T Grenfell
Dec 15, 2018·Physical Review Letters·Giovanni Petri, Alain Barrat
Dec 11, 2019·Proceedings of the National Academy of Sciences of the United States of America
Dec 5, 2018·Entropy·Joshua GarlandElizabeth Bradley

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Citations

Feb 10, 2019·Proceedings of the National Academy of Sciences of the United States of America·Cécile Viboud, Alessandro Vespignani
Jul 10, 2020·PLoS Computational Biology·Samuel V ScarpinoLauren Ancel Meyers
Jul 23, 2020·PLoS Computational Biology·Doina Bucur, Petter Holme
Dec 13, 2019·Royal Society Open Science·Tad A DallasTimothée Poisot
Mar 18, 2020·Scientific Reports·Loukas SamarasMiguel-Angel Sicilia
Aug 26, 2020·Proceedings of the National Academy of Sciences of the United States of America·John R GilesAmy Wesolowski
Apr 15, 2020·Nature Medicine·Marcello Ienca, Effy Vayena
Jul 28, 2020·International Journal of Environmental Research and Public Health·Rodney P Jones
Sep 16, 2020·Nonlinear Dynamics·Ziqi WangDidier Sornette
Mar 7, 2020·Science Advances·Donald R OlsonVirginia E Pitzer
May 8, 2020·Biology·Jacques DemongeotHervé Seligmann
Feb 15, 2020·Proceedings of the National Academy of Sciences of the United States of America·Rebecca KahnCaroline O Buckee
Aug 11, 2020·Journal of Complex Networks·Sen PeiHernán A Makse
Oct 11, 2020·Nature Communications·Fabio Della RossaMario di Bernardo
Nov 26, 2020·Scientific Reports·Andrés AbeliukKristina Lerman
Dec 9, 2020·Proceedings. Biological Sciences·Jesse R LaskyPeter B Adler
Feb 11, 2021·PLoS Computational Biology·Blake J M WilliamsLaurent Hébert-Dufresne
Jan 5, 2021·Royal Society Open Science·Levente Kriston
Feb 2, 2021·Sustainable Cities and Society·Miodrag ZivkovicFadi Al-Turjman
Mar 20, 2021·Physical Review. E·Michael NeuderJoshua Garland
Apr 3, 2021·Journal of Prevention & Intervention in the Community·Jan MohlmanCorey H Basch
May 19, 2021·Results in Physics·Leonardo H S FernandesBartolomeu Acioli-Santos
Dec 29, 2020·Annual Reviews in Control·Gemma MassonisAlejandro F Villaverde
Jul 6, 2021·Frontiers in Bioengineering and Biotechnology·Mohammad HosseinifardHamed Golmohammadi
Jul 14, 2021·Scientific Reports·Na ZhaoDuan-Bing Chen
Aug 18, 2021·Neural Computing & Applications·Supriya RahejaManoj Kumar
Sep 12, 2021·Journal of Theoretical Biology·Josephine N A TettehEsteban A Hernandez-Vargas
Dec 22, 2019·Revue D'épidémiologie Et De Santé Publique·P Le TurnierJ-F Guégan
May 4, 2020··Kristina LermanNegar Mokhberian

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