On the purpose of selective innervation of guinea-pig superior cervical ganglion cells

The Journal of Physiology
J W LichtmanJ W Yip

Abstract

Preganglionic axons arising from different levels of the mammalian spinal cord make preferential connexions with different classes of superior cervical ganglion cells (Langley, 1892, 1900; Njå & Purves, 1977a). For example, preganglionic axons from the first thoracic segment (T1) make relatively strong connexions with ganglion cells activating end-organs of the eye; conversely, axons arising from T4 selectively innervate ganglion cells projecting to the ear. In the present work we have asked whether this selectivity reflects the function of the pre- and post-synaptic cells, and aspect of their respective positions, or some other criterion. 1. End-organs with different functions at the same locus (the eye) respond to stimulation of the same ventral roots; end-organs of a single modality (hairs or blood vessels) at different positions, however, tend to be activated by different spinal segments. Thus the segmental innervation of ganglion cells is correlated with the position rather than the function of post-ganglionic targets. 2. The role of target position in ganglion cell innervation was examined directly by recording from neurones sending axons to different destinations. Superior cervical ganglion cells running dorso-medially i...Continue Reading

Citations

Feb 1, 1993·Current Opinion in Neurobiology·J R Sanes
Sep 1, 1984·Journal of the Autonomic Nervous System·R L Meckler, L C Weaver
Oct 7, 2000·Autonomic Neuroscience : Basic & Clinical·T BartschH J Häbler
May 26, 1997·The Journal of Comparative Neurology·E B CornbrooksC J Forehand
Jul 1, 1980·The Journal of Comparative Neurology·E Rubin, D Purves
Jun 15, 1989·The Journal of Comparative Neurology·A Ivanov, D Purves
Feb 20, 1981·The Journal of Comparative Neurology·B J Oldfield, E M McLachlan
Mar 1, 1993·Journal of Neurobiology·K LiestølA Njå

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