On the road towards tailor-made rhamnolipids: current state and perspectives

Applied Microbiology and Biotechnology
Andreas Wittgens, Frank Rosenau

Abstract

Rhamnolipids are biosurfactants with an enormous potential to replace or complement classic surfactants in industrial applications. They consist of one or two L-rhamnose residues linked to one or two 3-hydroxyfatty acids of various chain lengths, which can also contain unsaturated carbon-carbon bonds, yielding a wide variety of different structures each with its specific physicochemical properties. Since different applications of surfactants require specific tenside characteristics related to surface tension reduction, emulsification, and foaming etc., rhamnolipids represent a platform molecule which harbors an enormous potential to adopt tailor-made properties to meet a huge variety of demands of surfactants for food-, healthcare-, and biotechnological applications. We are here giving an overview on current technology to synthesize tailor-made rhamnolipids based on the biotechnological use of different enzymes responsible for rhamnolipid biosynthesis originating from different naturally rhamnolipid-producing microorganism. Furthermore, we present future strategies to determine the number of L-rhamnose and 3-hydroxyfatty acids as well as their specific chain lengths and unsaturations to produce customized rhamnolipids perfectly...Continue Reading

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Citations

Mar 19, 2019·Microbial Biotechnology·Ignacio Poblete-CastroPablo I Nikel
Apr 14, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zhuangzhuang LiShuang Li
Feb 6, 2020·Frontiers in Bioengineering and Biotechnology·Isabel BatorLars M Blank
Nov 17, 2020·Frontiers in Bioengineering and Biotechnology·Andreas Wittgens, Frank Rosenau
Mar 28, 2020·Current Opinion in Biotechnology·In Jin ChoSang Yup Lee
Mar 22, 2021·Bioresource Technology·Anoop R MarkandeSunita Varjani
Sep 25, 2021·Applied Microbiology and Biotechnology·Tengfei WangYi Jiang

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Methods Mentioned

BETA
chemical modifications
genetic modification
chemical modification

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