On the status of object concepts in aphasia

Brain and Language
H ChertkowV Whitehead

Abstract

While verbal comprehension is often impaired in aphasia due to left hemispheric damage, the status of nonverbal conceptual knowledge of objects remains controversial. We tested 16 aphasic subjects for their comprehension of concrete single words. Eight showed significant impairment on word-to-picture matching, when distractors were semantically and not just perceptually confusable. These 8 also made errors in answering verbal probe questions concerning the same items. When tested on a nonverbal pictorial version of the same probe questions, however, 3 of these 8 improved their performance to the level of normal controls. The other 5 showed continuing impairment in indicating responses to pictorial probes. These 5 showed no evidence of generalized intellectual impairment, and it is concluded that they demonstrated a comprehension deficit not limited to the verbal domain. Unlike the other aphasic patients, these latter 5 also had CT scan lesions extending into the posterior left temporal lobe (involving Brodmann's areas 22, 21, and 37). They were also more impaired in terms of general aphasia severity. It is suggested that a nonverbal (as well as verbal) semantic memory deficit occurs in a subgroup of patients with single word co...Continue Reading

References

Mar 1, 1979·Brain : a Journal of Neurology·E K Warrington, T Shallice
May 1, 1979·Brain and Language·M F SchwartzE M Saffran
Jan 1, 1979·The International Journal of Neuroscience·G GainottiC Caltagirone
Jan 1, 1977·Neuropsychologia·F M HatfieldJ Morton
Mar 1, 1978·Brain : a Journal of Neurology·A K Coughlan, E K Warrington
Jul 1, 1978·Brain and Language·P WhitehouseE Zurif
Jan 1, 1978·Perception·E K Warrington, A M Taylor
Jul 1, 1976·Brain and Language·H Goodglass, E Baker
Jul 1, 1976·Brain and Language·G Gainotti, M S Lemmo
Jun 1, 1976·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·H GoodglassN Ackerman
Nov 1, 1975·The Quarterly Journal of Experimental Psychology·E K Warrington
Mar 1, 1991·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·G MiceliA Caramazza
Mar 1, 1987·Brain and Language·M Koemeda-LutzE Meier
Apr 1, 1989·Brain : a Journal of Neurology·G Goldenberg
Aug 4, 1988·Nature·R A McCarthy, E K Warrington
Sep 1, 1986·Brain and Language·G GainottiG Miceli
Jan 1, 1972·Brain : a Journal of Neurology·E De RenziH Spinnler
Dec 1, 1969·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·M BartonD Urrea
Sep 1, 1984·Brain : a Journal of Neurology·E K Warrington, T Shallice
Dec 1, 1983·Brain : a Journal of Neurology·E K Warrington, R McCarthy
May 1, 1982·Brain and Language·S Wayland, J E Taplin
Oct 1, 1980·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·M Grossman
Jul 1, 1980·Brain and Language·E GroberJ Brown
Jul 1, 1980·Brain and Language·R CohenG Woll
Sep 1, 1962·Brain : a Journal of Neurology·E BAY

❮ Previous
Next ❯

Citations

Nov 6, 2003·Neuropsychology·Murray GrossmanDavid Alsop
Jan 7, 2010·Cerebral Cortex·Kimihiro NakamuraSeiji Ogawa
Dec 11, 2013·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Matthew A Lambon Ralph
May 6, 2003·Journal of Cognitive Neuroscience·J R BinderL Buchanan
Sep 3, 1999·Journal of Cognitive Neuroscience·S MurthaA Evans
Aug 24, 2007·Journal of Cognitive Neuroscience·Denise H WuAnjan Chatterjee
Mar 24, 2009·Journal of Cognitive Neuroscience·Gian Daniele ZanninoGiovanni A Carlesimo
Nov 29, 2007·Proceedings of the National Academy of Sciences of the United States of America·Kimihiro NakamuraSid Kouider
Jun 7, 2007·The Spanish Journal of Psychology·Sergei G Tsikunov, Svetlana G Belokoskova
Oct 18, 2011·Trends in Cognitive Sciences·Jeffrey R Binder, Rutvik H Desai
Feb 5, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Kimihiro NakamuraMasahiro Yamamoto
Oct 12, 2015·Brain : a Journal of Neurology·Hannah E ThompsonElizabeth Jefferies
May 25, 2010·Journal of Communication Disorders·Jamie ReillyJean Neils-Strunjas
Apr 29, 2008·Journal of Memory and Language·Elizabeth JefferiesMatthew A Lambon Ralph
May 8, 2007·Brain and Language·Catherine Hodgson, Matthew A Lambon Ralph
Jun 5, 2007·Behavioural Brain Research·Christine Whatmough, Howard Chertkow
Jun 13, 2006·Human Brain Mapping·Andrea MechelliCathy J Price
Oct 27, 2007·Neuropsychologia·Elizabeth JefferiesMatthew A Lambon Ralph
Sep 11, 2014·Cerebral Cortex·Gina F Humphreys, Matthew A Lambon Ralph
Dec 25, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Elizabeth Jefferies
Sep 22, 2009·Neuropsychologia·Elizabeth JefferiesMatthew A Lambon Ralph
Nov 20, 2001·Brain and Language·C AvilaJ M Gonzalez-Darder
Dec 14, 2011·NeuroImage·Leen Van DorenRik Vandenberghe
Nov 7, 2012·Neuropsychologia·Sofia Vallila-Rohter, Swathi Kiran
Oct 26, 2013·Neurocase·Marie-Therese ClercArmin von Gunten
Jun 30, 2016·Cognitive Neuropsychology·Tim Shallice
Jul 4, 2006·Brain : a Journal of Neurology·Elizabeth Jefferies, Matthew A Lambon Ralph
Mar 13, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Guido Gainotti

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