On using ethical principles of community-engaged research in translational science

Translational Research : the Journal of Laboratory and Clinical Medicine
Dmitry KhodyakovElizabeth Bromley

Abstract

The transfer of new discoveries into both clinical practice and the wider community calls for reliance on interdisciplinary translational teams that include researchers with different areas of expertise, representatives of health care systems and community organizations, and patients. Engaging new stakeholders in research, however, calls for a reconsideration or expansion of the meaning of ethics in translational research. We explored expert opinion on the applicability of ethical principles commonly practiced in community-engaged research (CEnR) to translational research. To do so, we conducted 2 online, modified-Delphi panels with 63 expert stakeholders who iteratively rated and discussed 9 ethical principles commonly used in CEnR in terms of their importance and feasibility for use in translational research. The RAND/UCLA appropriateness method was used to analyze the data and determine agreement and disagreement among participating experts. Both panels agreed that ethical translational research should be "grounded in trust." Although the academic panel endorsed "culturally appropriate" and "forthcoming with community about study risks and benefits," the mixed academic-community panel endorsed "scientifically valid" and "rea...Continue Reading

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Citations

Feb 26, 2016·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Dmitry KhodyakovLisa V Rubenstein
Dec 25, 2016·Journal of the American Medical Informatics Association : JAMIA·Dmitry KhodyakovKatherine K Kim
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Jul 12, 2017·Journal of Empirical Research on Human Research Ethics : JERHRE·Elizabeth BromleyDmitry Khodyakov
Jul 2, 2020·JAMIA Open·Carolyn PetersenRupa S Valdez
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Nov 15, 2019·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Dmitry KhodyakovNatalie Street
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May 18, 2021·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Karen L Fortuna

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