On visual hallucinations and cortical networks: a trans-diagnostic review.

Journal of Neurology
Rowena Carter, Dominic H Ffytche

Abstract

Our current clinical approach to visual hallucinations is largely derived from work carried out by Georges de Morsier in the 1930s. Now, almost a century after his influential papers, we have the research tools to further explore the ideas he put forward. In this review, we address de Morsier's proposal that visual hallucinations in all clinical conditions have a similar neurological mechanism by comparing structural imaging studies of susceptibility to visual hallucinations in Parkinson's disease, Alzheimer's disease, Dementia with Lewy bodies and schizophrenia. Systematic review of the literature was undertaken using PubMed searches. A total of 18 studies across conditions were identified reporting grey matter differences between patients with and without visual hallucinations. Grey matter changes were categorised into brain regions relevant to current theories of visual hallucinations. The distribution of cortical atrophy supports de Morsier's premise that visual hallucinations are invariably linked to aberrant activity within visual thalamo-cortical networks. Further work is required to determine by what mechanism these networks become predisposed to spontaneous activation, and whether the frontal lobe and hippocampal chang...Continue Reading

References

Jul 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·A BurnsR Levy
Apr 1, 1972·The American Journal of Psychiatry·M S McCabeG Winokur
Mar 1, 1996·The Journal of Nervous and Mental Disease·S Holroyd, P V Rabins
Apr 10, 1999·Nature Neuroscience·D H FfytcheS Williams
Jul 2, 1999·Brain : a Journal of Neurology·D H ffytche, R J Howard
Mar 4, 2000·The Journal of Neuropsychiatry and Clinical Neurosciences·S HolroydJ H Downs
Mar 29, 2000·Brain : a Journal of Neurology·G FénelonM Ziégler
Sep 1, 2000·Journal of the American Geriatrics Society·D AarslandK Laake
Jun 1, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·J Barnes, A S David
Oct 30, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·R HébertC Cohen
Jun 25, 2003·Brain : a Journal of Neurology·Marco CataniDominic H Ffytche
Dec 25, 2003·Lancet Neurology·Ian McKeithUNKNOWN International Psychogeriatric Association Expert Meeting on DLB
Sep 21, 2004·The British Journal of Ophthalmology·C S H TanK G Au Eong
Jun 7, 2005·Current Psychiatry Reports·Dominic H Ffytche
Oct 21, 2005·Neurology·I G McKeithUNKNOWN Consortium on DLB
Sep 9, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·David BurnRoger Lane
Oct 13, 2006·Archives of Neurology·Keith A JosephsRonald C Petersen
Nov 15, 2006·Neurology·James E GalvinJohn C Morris
Feb 3, 2007·Brain : a Journal of Neurology·Jennifer L WhitwellClifford R Jack
Jun 28, 2007·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·B Ramírez-RuizC Junqué
Aug 31, 2007·Cerebral Cortex·Ulrich EttingerSteven C R Williams
Jul 1, 2008·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Dominic H Ffytche
Sep 30, 2008·Journal of Neurology·Naroa Ibarretxe-BilbaoCarme Junqué
Jan 27, 2009·Current Opinion in Neurology·Dominic H ffytche
Jun 6, 2009·Nature Reviews. Neurology·Nico J DiederichChristopher G Goetz
Dec 8, 2009·Journal of Neurology, Neurosurgery, and Psychiatry·Naroa Ibarretxe-BilbaoEduardo Tolosa
Feb 23, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Cristina Sanchez-CastanedaCarme Junque
Oct 6, 2010·Movement Disorders : Official Journal of the Movement Disorder Society·Anne Marthe MeppelinkTeus van Laar
Jun 28, 2011·Journal of the Neurological Sciences·Naroa Ibarretxe-BilbaoEduardo Tolosa
Sep 29, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·James M ShineSimon J G Lewis
Apr 27, 2012·Cerebral Cortex·Renaud JardriDelphine Pins
Jun 1, 2012·Brain : a Journal of Neurology·Makoto UchiyamaEtsuro Mori
Jul 12, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Christopher G GoetzGlenn T Stebbins
Jul 31, 2013·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Nancy J DonovanUNKNOWN Alzheimer Disease Neuroimaging Initiative
Oct 10, 2013·Biological Psychiatry·Patrick S MurrayRobert A Sweet
Oct 24, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Hirohisa WatanabeGen Sobue
Feb 1, 2014·Brain : a Journal of Neurology·Jennifer G GoldmanChristopher G Goetz

❮ Previous
Next ❯

Citations

Jan 21, 2017·Nature Reviews. Neurology·Dominic H FfytcheDag Aarsland
Mar 21, 2017·Journal of Neurology, Neurosurgery, and Psychiatry·Dominic H FfytcheDag Aarsland
May 17, 2018·Expert Review of Neurotherapeutics·Byron CreeseClive Ballard
Mar 28, 2020·Journal of Neurology, Neurosurgery, and Psychiatry·John O'BrienDominic Ffytche
May 10, 2017·Frontiers in Neurology·Sara GarofaloGraham K Murray
Oct 15, 2019·Brain Communications·Rimona S WeilMichael D Fox
May 15, 2021·Practical Neurology·Rimona S Weil, A J Lees
May 26, 2021·Harvard Review of Psychiatry·Laura E GibbonsSejal B Shah
Aug 21, 2021·Frontiers in Neurology·Nicole GöbelRené M Müri
Oct 30, 2021·The Journal of Neuropsychiatry and Clinical Neurosciences·Gilles Fénelon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.