Once daily administration of pindolol in the treatment of hypertension

The Journal of International Medical Research
R C Dhatariya, A J Blowers

Abstract

An open study was carried out in general practice on patients with mild to moderate essential hypertension to assess the effectiveness of treatment with pindolol on a single daily dose regimen. In twenty-two previously untreated cases given a single daily dosage of pindolol (mean 13-0 mg, range 5 mg- 30 mg), adequate blood pressure control was achieved within five weeks and maintained in the nineteen patients examined at Week 25. Of eleven previously treated patients whose blood pressure was adequately controlled by divided daily doses of pindolol, a change-over to a single daily dosage of pindolol (mean 13-2 mg, range 10 mg-20 mg) did not result in any loss of control over a twenty-five week study period. Few side-effects were reported, and only one patient was withdrawn from the study.

References

May 1, 1977·Clinical Pharmacology and Therapeutics·Y M Traub, J B Rosenfeld
Jan 1, 1976·Upsala Journal of Medical Sciences·G Frithz
Jan 1, 1976·Current Medical Research and Opinion·A J Blowers, M A Melvin
Jan 1, 1976·The Journal of International Medical Research·J E Murphy
Sep 1, 1975·British Heart Journal·D Short
Aug 5, 1972·The Medical Journal of Australia·T O MorganA E Doyle
Sep 7, 1974·British Medical Journal·W E Miall, S Chinn
Aug 5, 1972·The Medical Journal of Australia·P Thorpe
Mar 24, 1973·British Medical Journal·P D Nigam, A S Malhotra
Feb 9, 1974·The Medical Journal of Australia·M C LaverP Kincaid-Smith
May 12, 1973·British Medical Journal·W H Aellig, K Saameli
Dec 7, 1968·British Medical Journal·F Post
Jan 25, 1969·British Medical Journal·A M Porter
Dec 1, 1967·The British Journal of Psychiatry : the Journal of Mental Science·E H Hare, D R Willcox

Related Concepts

Hypertensive Disease
Visken

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.