PMID: 773494Apr 24, 1976

Once-daily dosing with Atenolol in patients with mild or moderate hypertension

British Medical Journal
A P Douglas-Jones, J M Cruickshank

Abstract

Because of the difficulties patients have in adhering to their drug regimens a trial was performed in which patients with essential hypertension were given, in random order and for four weeks each, three different doses of atenolol to be taken once daily. Atenolol effectively decreased lying and standing blood pressures, and there was no difference between the effects of the three doses. The simplicity of the regimen, as well as atenolol's freedom from troublesome side effects, should be valuable in helping patients adhere to long-term treatment.

References

Oct 18, 1975·British Medical Journal·J C PetrieJ A Lewis
Apr 1, 1975·British Journal of Clinical Pharmacology·G E MarlinP Turner
Aug 2, 1973·The New England Journal of Medicine·B Blackwell

Citations

Jan 31, 1979·Psychopharmacology·A A LandauerF W Prott
Jan 1, 1982·European Journal of Clinical Pharmacology·W KiowskiF R Bühler
Jun 12, 1979·European Journal of Clinical Pharmacology·I Parvinen, E Paukkala
Jan 1, 1982·European Journal of Clinical Pharmacology·D S LawrenceJ M Cruickshank
May 17, 1978·European Journal of Clinical Pharmacology·J D FitzgeraldJ McAinsh
Apr 1, 1980·European Journal of Clinical Pharmacology·I R Edwards, O Else
Nov 27, 1978·European Journal of Clinical Pharmacology·A P Douglas-JonesA Lee
Jan 1, 1982·European Journal of Drug Metabolism and Pharmacokinetics·W Kirch, K G Görg
Jan 1, 1980·Pharmacology & Therapeutics·B N Prichard, C W Owens
Jan 1, 1992·Pharmacology & Therapeutics·G D Johnston
Jun 17, 1982·The New England Journal of Medicine·W H Frishman
Sep 30, 1993·The New England Journal of Medicine·G D Johnston
Jun 1, 1977·British Journal of Clinical Pharmacology·J D Harry, J Young
Oct 1, 1977·British Journal of Clinical Pharmacology·T A JeffersN P Barker
Apr 1, 1979·British Journal of Clinical Pharmacology·D N BatemanC T Dollery
May 27, 1978·British Medical Journal·T ReybrouckE Meulepas
Jul 31, 1976·British Medical Journal·S P Deacon, D Barnett
Jul 1, 1978·British Medical Journal·M S Knapp, A M Woolfson
Nov 1, 1977·Postgraduate Medical Journal·C M CastledenC F George
Oct 1, 1983·Postgraduate Medical Journal·G A Grell
May 1, 1978·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·P R ReevesM J Winrow
Jan 1, 1976·Current Medical Research and Opinion·R Gabriel
Jan 1, 1988·Clinical and Experimental Hypertension. Part A, Theory and Practice·L M WingD O Southgate
Jan 1, 1977·Current Medical Research and Opinion·N K GostickN P Barmer
Nov 10, 1983·The American Journal of Cardiology·U Thadani
Dec 1, 1981·British Journal of Clinical Pharmacology·S RasmussenP E Nielsen
May 1, 1986·Clinical Cardiology·J Pimenta, C B Pereira
Jan 1, 1982·Journal of Psychoactive Drugs·J Buffum
Jan 1, 1976·The Journal of International Medical Research·A M HarrisJ A Tweed
Jan 1, 1977·The Journal of International Medical Research·V H YajnikS H Patel
Aug 1, 1981·Circulation·M M Ibrahim, R Mossallam
Jun 1, 1982·British Journal of Clinical Pharmacology·R G Wilcox, J R Hampton
Jan 1, 1981·The Journal of International Medical Research·R D GordonG Row
Jul 1, 1983·Scottish Medical Journal·A P Forrest, R A Hawkins
Aug 1, 1981·British Journal of Clinical Pharmacology·J F De PlaenC Van Ypersele de Strihou
Jan 1, 1980·The Journal of International Medical Research·J Tuomilehto, A Nissinen
Jan 1, 1978·Acta Medica Scandinavica·F GyntelbergB Harvald

Related Concepts

Tenormin
Diastolic Blood Pressure
Clinical Trials
Pulse Rate
Hypertensive Disease
Placebos
Propanolamines

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.