Oncocytic mania: a review of oncocytic lesions throughout the body

Journal of Endocrinological Investigation
F GuaraldiPatrizio Caturegli

Abstract

Oncocytic lesions are characterized pathologically by an abundance of oncocytes, that is by enlarged, eosinophilic, and finely granular cells enriched in mitochondria. They can arise in numerous organs and tissues, often in endocrine glands, and have been associated with hyperplasia, autoimmunity, and neoplasia. The causes and mechanisms that transform a normal cell into an oncocyte remain to be elucidated. Aim of this article is to review the most common oncocytic lesions, highlighting their key pathological features and clinical significance.

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Citations

Jan 18, 2014·Autoimmunity Reviews·P CaturegliN R Rose
Feb 17, 2019·Archives of Pharmacal Research·Min-Kyue Shin, Jae-Ho Cheong
May 29, 2021·BMJ Case Reports·Lee Rima MadiYael Levy-Shraga

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