PMID: 7581156Aug 1, 1995Paper

Oncocytic metaplasia of bile duct epithelium in hepatic GVHD

Bone Marrow Transplantation
J BlighN Walker

Abstract

A 15-year-old female underwent matched unrelated BMT for chemotherapy resistant ALL. She died 3 months later from septicaemia complicating grade IV GVHD. Light and electron microscopic examination of the post-mortem liver confirmed GVHD and showed oncocytic metaplasia of interlobular bile duct epithelium. We report that oncocytic metaplasia of bile duct epithelium is part of the pathological spectrum of hepatic GVHD.

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