PMID: 8940996Dec 1, 1996Paper

Oncocytomas of the submandibular gland. A series of 22 cases and a review of the literature

Cancer
L D ThompsonG L Ellis

Abstract

Oncocytomas are benign salivary gland neoplasms that represent approximately 1.5% of all salivary gland tumors. Oncocytomas of the submandibular gland, however, are decidedly uncommon. Twenty-two cases of submandibular gland oncocytomas from the files of the Oral and Otolaryngic Tumor Registries of the Armed Forces Institute of Pathology were reviewed, and analysis of the histologic criteria, histochemical and immunohistochemical reactions, and ultrastructural and clinical follow-up data was performed. The patients included 11 females and 11 males, age 21-88 years, with a mean age at presentation of 58.7 years. Clinically, the tumors were generally asymptomatic masses in the submandibular gland that increased in size over a period ranging from several weeks to 20 years and were occasionally associated with pain (n = 9). The tumors ranged in greatest dimension from 0.7 to 7 cm and were circumscribed to encapsulated. Histologically, the tumors were characterized by large epithelial cells with eosinophilic, granular cytoplasm. The cytoplasm stained positively with stains used to demonstrate mitochondria (phosphotungstic acid-hematoxylin, Novelli, Cresylecht violet V, and Kluver-Barrera Luxol fast blue stains). Immunohistochemical ...Continue Reading

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Citations

Mar 23, 2011·International Journal of Oral and Maxillofacial Surgery·Mehrnoosh Dastaran, Arun Chandu
Aug 4, 2009·Pathology, Research and Practice·Christoph WeilerStephan Ihrler
Dec 10, 1998·Annals of Diagnostic Pathology·G L Ellis
Sep 29, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Alexander D RapidisGregory Faratzis
Aug 21, 2013·Ultrastructural Pathology·Jacques GilloteauxJack L Summers
Dec 25, 2015·International Journal of Surgical Pathology·Masamitsu TamaiRumi Kambara
Apr 17, 2010·AJNR. American Journal of Neuroradiology·T J Tan, T Y Tan
Jun 27, 2008·Clinical Nuclear Medicine·Rathan M SubramaniamPatrick J Peller
Nov 9, 2006·Virchows Archiv : an International Journal of Pathology·Hagen B E Klieb, Bayardo Perez-Ordoñez
Jun 1, 2007·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·K R V SakthikumarK Dineshkumar
Sep 26, 2012·The Journal of Obstetrics and Gynaecology Research·Takashi YamadaHisanori Minakami
Jul 31, 1998·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M NakadaT Yoshino

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