Oncologic outcome and continence recovery after laparoscopic radical prostatectomy: 3 years' follow-up in a "second generation center"

European Urology
Stefano GalliFranco Gaboardi

Abstract

Laparoscopic radical prostatectomy in major centers guarantees oncologic and functional results equal to open procedures. In our institution this operation was introduced in 2001 after an adequate training in laparoscopic surgery. We report the oncologic and functional results after 3 years of experience. We considered our first 150 patients that had undergone transperitoneal laparoscopic radical prostatectomy. The following parameters were prospectively collected and analyzed: pathological findings, surgical margins, surgical time, blood loss, hospital stay, catheterization, complications, oncologic follow-up and continence. Single positive surgical margins were observed in 26 patients (17.3%) and multiple positive margins in 15 patients (10%). The rates of positive margins in organ confined tumors (pT2a/b) were 11.3%. Preoperative PSA>10 ng/ml (Chi-square p<0.01), pathological stage>pT2 (Chi-square p<0.001) and Gleason score>6 (Chi-square p<0.01) were significantly correlated with positive margins. Major complications occurred in 16 patients (10.7%). The total recurrence rate is 11.7%. The continence rate at 12 months is 91.7%.with 44.3% of patients completely continent at the moment of catheter removal. Laparoscopic radical ...Continue Reading

References

May 1, 1997·The Journal of Urology·O DillioglugilP T Scardino
May 8, 2000·The Journal of Urology·B Guillonneau, G Vallancien
Dec 18, 2001·The Journal of Urology·Bertrand GuillonneauGuy Vallancien
Apr 11, 2003·The Journal of Urology·Jens RassweilerThomas Frede
Jun 26, 2004·BJU International·Laurent SalomonClaude C Abbou
Jun 26, 2004·BJU International·Laurent SalomonClaude C Abbou

❮ Previous
Next ❯

Citations

Sep 11, 2008·World Journal of Urology·Evangelos LiatsikosJens-Uwe Stolzenburg
Jul 22, 2009·Journal of Endourology·Jens-Uwe StolzenburgEvangelos N Liatsikos
Dec 1, 2011·Journal of Robotic Surgery·Charles-Henry RochatUsha Kreaden
Apr 5, 2011·European Urology·Ricarda M BauerChristian G Stief
Apr 13, 2010·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·O SimoninG Karsenty
Oct 9, 2012·International Journal of Urology : Official Journal of the Japanese Urological Association·Akio HoshiToshiro Terachi
Apr 12, 2016·Neurourology and Urodynamics·X BiardeauJ Corcos
Oct 29, 2009·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Mirandolino B MarianoIsidoro H Goldraich
May 5, 2009·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Pierluigi BoveGiuseppe Vespasiani
Feb 1, 2018·World Journal of Urology·Andrew Jason CohenJaclyn Milose
Dec 3, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Chunxia WangSheng Tai
Dec 22, 2009·Neurourology and Urodynamics·Sender HerschornUNKNOWN Committee of the International Consultation on Incontinence
Feb 27, 2018·Current Urology Reports·Maria Arcila-Ruiz, Benjamin M Brucker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.