Oncologic outcomes after resection of para-aortic lymph node metastasis in left-sided colon and rectal cancer.

PloS One
Junichi SakamotoShin Fujita

Abstract

The optimal surgical management strategy for para-aortic lymph node (PALN) metastasis has not attracted as much attention as surgery for liver or lung metastasis. The purpose of this retrospective study was to evaluate the oncologic outcomes after synchronous resection of PALN metastasis in left-sided colon and rectal cancer. Between January 1986 and August 2016, 29 patients with pathologically positive PALN metastases who underwent curative resection at our hospital were retrospectively reviewed. We examined clinicopathological characteristics, long-term oncologic outcomes, and factors related to favorable prognosis in these patients. The 3-year overall survival and recurrence-free survival (RFS) rates were 50.5% and 17.2%, respectively. In total, 6 (20.7%) patients experienced no recurrence in the 3 years after surgery, while postoperative complications were seen in 9 (31.0%) patients. The 3-year RFS rate was significantly better in the pM1a group than in the pM1b/pM1c group (26.3% and 0.0%, respectively, p = 0.032). PALN dissection for patients without other organ metastases in left-sided colon or rectal cancer is a good indication as it is for liver and lung metastasis.

References

Feb 1, 1994·Diseases of the Colon and Rectum·A LeggeriA Turoldo
Apr 1, 1999·The British Journal of Surgery·T LehnertC Herfarth
May 30, 2002·Annals of Surgery·Michael A ChotiJohn L Cameron
Mar 1, 1959·Diseases of the Colon and Rectum·M W STEARNS, M R DEDDISH
Feb 28, 2006·Journal of the American College of Surgeons·Shimul A ShahAlice C Wei
Jun 17, 2010·Diseases of the Colon and Rectum·Najjia Mahmoud, Kelli Bullard Dunn
Oct 18, 2011·International Journal of Clinical Oncology·Toshiaki WatanabeUNKNOWN Japanese Society for Cancer of the Colon and Rectum
Jun 29, 2014·International Journal of Colorectal Disease·Shin Fujita
Apr 7, 2017·International Journal of Colorectal Disease·Nozomu NakaiAkinobu Furutani
Jul 15, 2017·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Sung Uk BaeNam Kyu Kim

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Citations

Nov 28, 2021·International Journal of Clinical Oncology·Hiroaki NozawaSoichiro Ishihara

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Methods Mentioned

BETA
surgical resection
dissection
dissections

Software Mentioned

EZR
R Commander
R

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