Oncological and functional outcomes of sexual function-preserving cystectomy compared with standard radical cystectomy in men: A systematic review

Urologic Oncology
Virginia HernándezMaria J Ribal

Abstract

Different sexual function-preserving surgical techniques aimed at improving voiding and sexual function in patients undergoing radical cystectomy for bladder cancer have been described. The objective of this systematic review is to determine the effect of sexual function-preserving cystectomy (SPC) on functional and oncological outcomes. Relevant databases were searched covering the time frame 2000 to 2015. All publications presenting data on any type of SPC reporting oncological or functional outcomes with a minimum follow-up of 1 year were identified. Comparative studies including a minimum of 30 patients and single-arm case series with a minimum of 50 patients were selected. No language restrictions were applied. In a total of 8,517 identified abstracts, 12 studies were eligible for inclusion. SPC described included prostate-, capsule-, seminal vesicle, and nerve-sparing techniques. Local recurrence ranged from 1.2% to 61.1% (vs. 16.0%-55.0% in the control group) and metastatic disease from 0% to 33.3% (vs. 33.0%). No differences were found in comparative studies reporting oncological outcomes. Postoperative potency was significantly better in the SPC groups in 6 studies comparing sexual function-preserving cystectomy vs. ra...Continue Reading

Citations

Nov 11, 2018·Current Urology Reports·Sumeet K Bhanvadia
Sep 12, 2020·BJU International·Fabian P Stangl, George N Thalmann
Feb 6, 2021·Seminars in Oncology Nursing·Ulla Nordström JoensenAlicia Martin Poulsen
Nov 20, 2020·World Journal of Urology·Berfin ErdoganGuido Müller
Jul 28, 2020·The Journal of Sexual Medicine·Mary E WestermanNeema Navai
May 8, 2021·Hematology/oncology Clinics of North America·Vivek Venkatramani, Dipen Jaysukhlal Parekh
Jul 1, 2021·Therapeutic Advances in Urology·Alessandro IzzoSisto Perdonà

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