Oncological evaluation of prostate sparing cystectomy: the Montsouris long-term results

The Journal of Urology
Francois RozetGuy Vallancien

Abstract

Prostate sparing cystectomy provides an alternative therapeutic option in highly selected patients with invasive bladder cancer who wish to avoid the significant functional side effects of traditional surgery. Concern exists regarding the oncological safety of this technique especially with regard to the presence of prostatic urothelial cancer and incidental prostate adenocarcinoma. We present the long-term oncological outcomes of a large series of patients treated at a single institution. Between October 1992 and June 2004 a total of 117 patients were selected for prostate sparing cystectomy after meeting the inclusion criteria. Nine patients underwent radical cystoprostatectomy after prostate urothelial carcinoma was diagnosed intraoperatively. Long-term oncological results (2 years minimum followup [mean 55 months]) are presented here for the remaining patients. The rate of local and distant recurrence was 4.7% and 34%, respectively, at 20 months. Overall survival at 5 years in our study was 67%, and 5-year disease-free survival rates were 77% for pT2 N0 or less, 44% for pT3 N0 or greater and 22% for pN+ disease. Of 6 patients found to have prostate adenocarcinoma in transurethral prostate resection specimens 1 was treated w...Continue Reading

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Citations

Jan 27, 2012·Der Urologe. Ausg. A·A HeidenreichD Pfister
Oct 31, 2013·Annals of Surgical Oncology·Géraldine PignotUNKNOWN Oncologic Committee of the French Association of Urology
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Nov 30, 2013·The Journal of Urology·Laura S MertensSimon Horenblas
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Feb 26, 2020·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·M RouprêtA Méjean

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