Oncology and Cardiac Rehabilitation: An Underrated Relationship

Journal of Clinical Medicine
Venturini EFrancesco Giallauria

Abstract

Cancer and cardiovascular diseases are globally the leading causes of mortality and morbidity. These conditions are closely related, beyond that of sharing many risk factors. The term bidirectional relationship indicates that cardiovascular diseases increase the likelihood of getting cancer and vice versa. The biological and biochemical pathways underlying this close relationship will be analyzed. In this new overlapping scenario, physical activity and exercise are proven protective behaviors against both cardiovascular diseases and cancer. Many observational studies link an increase in physical activity to a reduction in either the development or progression of cancer, as well as to a reduction in risk in cardiovascular diseases, a non-negligible cause of death for long-term cancer survivors. Exercise is an effective tool for improving cardio-respiratory fitness, quality of life, psychological wellbeing, reducing fatigue, anxiety and depression. Finally, it can counteract the toxic effects of cancer therapy. The protection obtained from physical activity and exercise will be discussed in the various stages of the cancer continuum, from diagnosis, to adjuvant therapy, and from the metastatic phase to long-term effects. Particul...Continue Reading

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Citations

Mar 23, 2021·World Journal of Clinical Cases·Petr WinnigeLadislav Batalik
Feb 3, 2021·Panminerva Medica·Elio VenturiniFrancesco Giallauria
Jun 18, 2021·Journal of Oncology·Filadelfiya ZvinovskiAllison M Quick

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