PMID: 19149661Jan 20, 2009Paper

Oncomirs: from tumor biology to molecularly targeted anticancer strategies

Mini Reviews in Medicinal Chemistry
Simone MocellinPierluigi Pilati

Abstract

Deregulation of microRNA (miRNA) promotes carcinogenesis, as these molecules can act as oncogenes or tumor suppressor genes. Here we provide an overview of miRNA biology, discuss the most recent findings on miRNA and cancer development/progression, and report on how tumor-related miRNAs (oncomirs) are being used to develop novel cancer specific therapeutic approaches.

Citations

Nov 6, 2009·PloS One·Kay Sin TanKandiah Jeyaseelan
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