Oncosurgical and reconstructive concepts in the treatment of soft tissue sarcomas: a retrospective analysis

Archives of Orthopaedic and Trauma Surgery
Holger BannaschG Björn Stark

Abstract

Patients with soft tissue sarcomas are initially treated in community hospitals and in the private practice setting in the majority of cases. Thus, this disease entity is initially treated by surgeons with limited experience and expertise regarding the complex and demanding therapeutic regimen necessary to address this distinct group of malignancies. A retrospective analysis was conducted with a particular focus on factors affecting patient outcome, oncosurgical intervention, and plastic surgical reconstruction. A total of 75 patients were included in the study. Only 66% of all patients presented with a primary tumor. The remaining 34% presented with either local recurrence or distant metastasis. The oncosurgical procedure most commonly performed was wide excision (69%). However, amputation was unavoidable in 7% of cases. Single-step reconstruction included primary closure (19%), skin grafting (19%), local fascio- or myocutaneous flap transfer (31%), as well as free flap transfer (31%). 17 patients (20%) have deceased due to their underlying disease. Yet another 10% are alive with evidence of residual tumor. Kaplan-Meier analysis displayed significant differences in overall survival rate depending on disease stage upon initial ...Continue Reading

References

May 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P W PistersM F Brennan
Jan 24, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J C YangS A Rosenberg
Jun 1, 2001·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H U SteinauP Vogt
Jan 12, 2002·Plastic and Reconstructive Surgery·Howard N LangsteinGeoffrey L Robb
Sep 5, 2002·Cancer·Patrick P LinAlan W Yasko
Jan 7, 2004·Plastic and Reconstructive Surgery·Pentscho PopovCarl Blomqvist
Mar 17, 2004·Clinical Orthopaedics and Related Research·Noriyoshi KawaguchiYasushi Matsushita
Jul 28, 2004·Plastic and Reconstructive Surgery·John Y KimDavid W Chang

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Citations

Mar 10, 2009·Archives of Orthopaedic and Trauma Surgery·Dietmar UlrichNorbert Pallua
Feb 18, 2011·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Juan María Viñls ViñalsJosé Antonio Narváez García
Mar 18, 2011·Medicina clínica·Xavier García Del MuroUNKNOWN Grupo Español de Investigación en Sarcomas (GEIS)
Sep 11, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Arash MomeniHolger Bannasch
Jun 2, 2011·Microsurgery·Vincenzo PennaHolger Bannasch
Aug 8, 2015·Molecular Cancer·Alba FrickeDavid Braig
Jun 12, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S KangH-S Kim
Jan 20, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Olaf MagerkurthDavid A Jamadar
Oct 27, 2015·World Journal of Surgical Oncology·Georgios KoulaxouzidisG Björn Stark
Dec 19, 2019·Frontiers in Oncology·Johannes ZellerSteffen U Eisenhardt
Feb 3, 2011·Deutsches Ärzteblatt International·Holger BannaschG Björn Stark
Sep 14, 2011·Deutsches Ärzteblatt International·Holger Bannasch

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