One case report of anti-JK1 antibody undetected on plasma sample

Transfusion clinique et biologique : journal de la Société française de transfusion sanguine
B ClavierM Joussemet

Abstract

The sensitivity of the detection of irregular antibodies (DIA) is one of the fundamental bases of transfusion safety. Its implementation is specified in accordance with a very specific framework that allows the use of serum or plasma. The case reported here points out a failure to detect irregular antibodies in plasma sample. Thus a low intensity anti-JK1 antibody detected and identified in serum slipped through unnoticed in plasma. The difficulties to detect and identify this antibody, well-known as a deceptive and dangerous one, are being discussed in order to better assess the limitations of DIA.

Citations

Jan 24, 2012·La Revue de médecine interne·F de CharryP Debourdeau

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