One Hundred Twenty-Day Mortality Rates for Hip Fracture Patients with COVID-19 Infection.

Clinics in Orthopedic Surgery
Tobenna J OputaNorth West COVID NOF Study Group

Abstract

Increased 30-day mortality rates have been reported for patients with hip fractures and a concurrent diagnosis of coronavirus disease 19 (COVID-19) infection. Due to nosocomial spread of infection and the variable incubation period with the virus, follow-up past 30 days after injury is required to evaluate the true mortality amongst these patients. We aim to assess 120-day mortality rates in hip fracture patients with COVID-19 infection and compare this to hip fracture patients without COVID-19 infection presenting during the same time period. This is a retrospective multicenter review of all patients aged ≥ 60 years admitted with a fractured neck of femur between March 5 and April 5, 2020, at nine U.K. trauma units. COVID-19 status, demographic data, comorbidities, and date of death (if applicable) were collected. Data were collected for 265 hip fracture patients. Forty-six patients (17.4%) tested positive for COVID-19 infection. There were no significant differences in age or Charlson comorbidity score between those with or without COVID-19. Those with COVID-19 infection were more likely to be male (p = 0.01). Patients with COVID-19 had a 30-day mortality of 35% versus 10% in patients without (p < 0.01). One hundred twenty-da...Continue Reading

References

Apr 2, 2008·The Journal of Bone and Joint Surgery. British Volume·G HoltA Gregori
May 2, 2018·The Journal of Bone and Joint Surgery. American Volume·Luke FarrowPhyo K Myint
Jan 4, 2019·Annals of the Royal College of Surgeons of England·T J WaltonB A Rogers
Jul 16, 2019·Orthopaedics & Traumatology, Surgery & Research : OTSR·Adrien DelaveauTanguy Vendeuvre
Oct 11, 2019·Der Unfallchirurg·Carsten SchoenebergUNKNOWN AltersTraumaRegister DGU
Apr 4, 2020·BMJ : British Medical Journal·Michael Day
May 6, 2020·The European Respiratory Journal·Xiaorong WangZhancheng Gao
May 8, 2020·The Journal of Bone and Joint Surgery. American Volume·Bobin MiGuohui Liu
May 14, 2020·BMJ : British Medical Journal·Jessica WatsonJohn E Brush
Jul 8, 2020·The Bone & Joint Journal·Babar KayaniFares S Haddad
Sep 5, 2020·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Leanne DupleyUNKNOWN North West COVID NOF Study Group
Dec 11, 2020·PloS One·Ingrid Arevalo-RodriguezJavier Zamora

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.