One of the most well-established age-related changes in neural activity disappears after controlling for visual acuity

NeuroImage
Fábio H G PortoKirk R Daffner

Abstract

Numerous studies using a variety of imaging techniques have reported age-related differences in neural activity while subjects carry out cognitive tasks. Surprisingly little attention has been paid to the potential impact of age-associated changes in sensory acuity on these findings. Studies in the visual modality frequently report that their subjects had "normal or corrected- to-normal vision." However, in most cases, there is no indication that visual acuity was actually measured, and it is likely that the investigators relied largely on self-reported visual status of subjects, which is often inaccurate. We investigated whether differences in visual acuity influence one of the most commonly observed findings in the event-related potentials literature on cognitive aging, a reduction in posterior P3b amplitude, which is an index of cognitive decision-making/updating. Well-matched young (n=26) and old adults (n=29) participated in a visual oddball task. Measured visual acuity with corrective lenses was worse in old than young adults. Results demonstrated that the robust age-related decline in P3b amplitude to visual targets disappeared after controlling for visual acuity, but was unaffected by accounting for auditory acuity. Pat...Continue Reading

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Citations

Aug 4, 2016·Neuroscience and Biobehavioral Reviews·Zachary A Monge, David J Madden
Jan 17, 2020·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Ted MaldonadoJessica A Bernard
Jun 11, 2019·Workplace Health & Safety·Stephanie HammondKaren Heaton
Dec 6, 2020·Neuroscience and Biobehavioral Reviews·Mónica Muiños, Soledad Ballesteros
Nov 7, 2020·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Adam R BilligKirk R Daffner

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